Ayas, Fahriye Yonca, Özcebe, Lütfiye Hilal · Sleep & breathing = Schlaf & Atmung · 2025 · DOI
This study looked at how fatigue, sleep quality, and daytime sleepiness are connected in workplace employees. Researchers found that when people have poor sleep quality or don't sleep enough hours, they tend to experience more fatigue and daytime sleepiness—and these problems appear to affect each other in a cycle. The study suggests that addressing sleep problems may be important for reducing fatigue and improving workplace safety.
ME/CFS patients frequently report poor sleep quality, sleep disorders, and daytime dysfunction alongside fatigue. This study's documentation of interconnected relationships among sleep quality, sleep duration, daytime sleepiness, and fatigue severity may help validate these overlapping symptoms in working populations and underscore the need for integrated assessment of sleep and fatigue in chronic illness.
This study does not establish causation—it cannot determine whether poor sleep causes fatigue, fatigue causes poor sleep, or a third factor drives both. The cross-sectional design captures associations at a single timepoint and cannot rule out confounding variables. The study does not specifically diagnose or characterize ME/CFS or other post-exertional malaise conditions; findings are from a general working population with varying sleep and fatigue levels.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Ayas, Fahriye Yonca & Özcebe, Lütfiye Hilal (2025). The relationship between fatigue, sleep quality, and sleep deprivation.. Sleep & breathing = Schlaf & Atmung. https://doi.org/10.1007/s11325-024-03231-w
BibTeX
@article{mecfsatlas-ayas-2025-relationship-between,
author = {Ayas, Fahriye Yonca and Özcebe, Lütfiye Hilal},
title = {The relationship between fatigue, sleep quality, and sleep deprivation.},
journal = {Sleep & breathing = Schlaf & Atmung},
year = {2025},
doi = {10.1007/s11325-024-03231-w},
note = {PubMed: 39804542},
url = {https://www.mecfsatlas.com/evidence/ayas-2025-relationship-between},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-26. https://www.mecfsatlas.com/evidence/ayas-2025-relationship-between
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