Li, Zhijun, Ji, Rong, Yan, Chaoqun et al. · Zhongguo zhen jiu = Chinese acupuncture & moxibustion · 2024 · DOI
Researchers tested whether massaging a specific acupuncture point called Shenque (located on the abdomen) could help people with chronic fatigue syndrome. Patients in the treatment group received 10-minute massages three times a week for four weeks, while the control group received no treatment. The treatment group showed meaningful improvements in fatigue and sleep quality compared to the control group.
Sleep disturbance and fatigue are core ME/CFS symptoms that significantly impair quality of life. This study explores a non-pharmacological intervention that, if validated, could offer ME/CFS patients an accessible treatment option with minimal side effects. Understanding whether acupoint massage provides genuine therapeutic benefit or placebo effects is important for developing evidence-based symptom management strategies.
This study does not prove that acupoint massage specifically works for ME/CFS, as it lacks blinding and a true placebo control—improvements could reflect placebo effects, natural variation, or non-specific attention effects. The study design cannot establish whether benefits persist beyond the four-week treatment period or whether they generalize to other CFS populations. The mechanism of action remains unexplained.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Li, Zhijun, Ji, Rong, Yan, Chaoqun, Chen, Yichao, Cao, Zimin, & Wang, Jun (2024). Acupoint massage at Shenque (CV 8) for chronic fatigue syndrome: a randomized controlled trial.. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. https://doi.org/10.13703/j.0255-2930.20230307-0002
BibTeX
@article{mecfsatlas-li-2024-acupoint-massage,
author = {Li, Zhijun and Ji, Rong and Yan, Chaoqun and Chen, Yichao and Cao, Zimin and Wang, Jun},
title = {Acupoint massage at Shenque (CV 8) for chronic fatigue syndrome: a randomized controlled trial.},
journal = {Zhongguo zhen jiu = Chinese acupuncture & moxibustion},
year = {2024},
doi = {10.13703/j.0255-2930.20230307-0002},
note = {PubMed: 38191162},
url = {https://www.mecfsatlas.com/evidence/li-2024-acupoint-massage},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-26. https://www.mecfsatlas.com/evidence/li-2024-acupoint-massage
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