Orji, Nneka C, Cox, Ingrid A, Jason, Leonard A et al. · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024 · DOI
This study measured how much ME/CFS affects quality of life in 198 Australian people with the condition. Researchers used three different questionnaires to assess health-related quality of life and found that people with ME/CFS reported significantly lower quality of life scores compared to healthy people. As people's fatigue and disability became more severe, their quality of life scores dropped further.
This research quantifies the profound impact ME/CFS has on quality of life, providing critical data for healthcare planning, policy-making, and clinical trial design. Identifying which measurement tools best capture ME/CFS-related quality of life changes improves future research precision and ensures patients' experiences are accurately reflected in medical assessments.
This study does not prove that any particular treatment improves quality of life, nor does it establish causal relationships between specific ME/CFS symptoms and quality of life outcomes. As a cross-sectional survey, it captures a single point in time and cannot demonstrate how quality of life changes over the disease course. The results apply specifically to the Australian population and may not generalize to other countries or demographics.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Orji, Nneka C, Cox, Ingrid A, Jason, Leonard A, Chen, Gang, Zhao, Ting, Rogerson, Melissa J, et al. (2024). Assessing health state utilities for people with myalgic encephalomyelitis/chronic fatigue syndrome in Australia using the EQ-5D-5L, AQoL-8D and EQ-5D-5L-psychosocial instruments.. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. https://doi.org/10.1007/s11136-023-03498-8
BibTeX
@article{mecfsatlas-orji-2024-assessing-health,
author = {Orji, Nneka C and Cox, Ingrid A and Jason, Leonard A and Chen, Gang and Zhao, Ting and Rogerson, Melissa J and Kelly, Ryan M and Wills, Karen and Hensher, Martin and Palmer, Andrew J and de Graaff, Barbara and Campbell, Julie A},
title = {Assessing health state utilities for people with myalgic encephalomyelitis/chronic fatigue syndrome in Australia using the EQ-5D-5L, AQoL-8D and EQ-5D-5L-psychosocial instruments.},
journal = {Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation},
year = {2024},
doi = {10.1007/s11136-023-03498-8},
note = {PubMed: 37561337},
url = {https://www.mecfsatlas.com/evidence/orji-2024-assessing-health},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-29. https://www.mecfsatlas.com/evidence/orji-2024-assessing-health
Contribute
Private, reviewed by a human. Not a public comment thread.