Pajediene, Evelina, Bileviciute-Ljungar, Indre, Friberg, Danielle · The clinical respiratory journal · 2018 · DOI
This study looked at sleep problems in people with chronic fatigue by using a sleep monitoring test called polysomnography. Researchers found that more than half of the fatigued patients who also felt excessively sleepy had treatable sleep disorders like sleep apnea, restless legs, or periodic leg movements. The authors suggest that people with these symptoms should be tested for sleep disorders and treated before being diagnosed with ME/CFS, since fixing the sleep problem might help with fatigue.
This research highlights an important clinical issue: many people diagnosed with ME/CFS may actually have treatable sleep disorders contributing to their fatigue. Identifying and treating these underlying sleep problems could significantly improve patient outcomes and may prevent misdiagnosis. The study supports the need for comprehensive sleep evaluation as part of the diagnostic workup for chronic fatigue.
This study does not establish that sleep disorders cause ME/CFS or that treating them cures the condition. It is a cross-sectional snapshot and cannot prove causality or show whether treating these sleep disorders actually improves fatigue in ME/CFS patients. Additionally, the study only examined patients with excessive daytime sleepiness, so findings may not apply to all ME/CFS patients.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Pajediene, Evelina, Bileviciute-Ljungar, Indre, & Friberg, Danielle (2018). Sleep patterns among patients with chronic fatigue: A polysomnography-based study.. The clinical respiratory journal. https://doi.org/10.1111/crj.12667
BibTeX
@article{mecfsatlas-pajediene-2018-sleep-patterns,
author = {Pajediene, Evelina and Bileviciute-Ljungar, Indre and Friberg, Danielle},
title = {Sleep patterns among patients with chronic fatigue: A polysomnography-based study.},
journal = {The clinical respiratory journal},
year = {2018},
doi = {10.1111/crj.12667},
note = {PubMed: 28752613},
url = {https://www.mecfsatlas.com/evidence/pajediene-2018-sleep-patterns},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-26. https://www.mecfsatlas.com/evidence/pajediene-2018-sleep-patterns
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