Qi, Yuangang, Song, Shoujiang, Dou, Zhiqiang et al. · Zhongguo zhen jiu = Chinese acupuncture & moxibustion · 2017 · DOI
This study tested whether combining a traditional Chinese herbal medicine (Chaihu Longgu Muli decoction) with acupuncture works better than the herb alone for chronic fatigue syndrome. Sixty patients received either the herbal treatment for one month, or the same herbs plus 30-minute acupuncture sessions at specific back points over three treatment courses. Both groups improved, but the combination of herbs and acupuncture produced greater reductions in fatigue and anxiety than the herb alone.
For ME/CFS patients seeking integrated treatment options, this study suggests that combining traditional herbal medicine with targeted acupuncture may produce greater symptom relief than either approach alone. Understanding whether combination therapies offer additive benefits could help patients and clinicians design more effective treatment plans, particularly in healthcare systems where these modalities are available.
This study does not establish whether the improvements were due to the specific herbal formula, the acupuncture, or general treatment effects (placebo response, therapeutic attention, natural recovery). The lack of a true placebo or standard-care control group means we cannot rule out non-specific healing effects. The findings also cannot be generalized beyond the study population or confirm these results would replicate in other geographic or healthcare contexts.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Qi, Yuangang, Song, Shoujiang, Dou, Zhiqiang, Chen, Jin, He, Guiying, Zhang, Lijun, et al. (2017). [<i>Chaihu Longgu Muli</i> decoction combined with acupuncture at back-<i>shu</i> points for chronic fatigue syndrome].. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. https://doi.org/10.13703/j.0255-2930.2017.11.013
BibTeX
@article{mecfsatlas-qi-2017-chaihu-longgu,
author = {Qi, Yuangang and Song, Shoujiang and Dou, Zhiqiang and Chen, Jin and He, Guiying and Zhang, Lijun and Yao, Jincheng},
title = {[<i>Chaihu Longgu Muli</i> decoction combined with acupuncture at back-<i>shu</i> points for chronic fatigue syndrome].},
journal = {Zhongguo zhen jiu = Chinese acupuncture & moxibustion},
year = {2017},
doi = {10.13703/j.0255-2930.2017.11.013},
note = {PubMed: 29354956},
url = {https://www.mecfsatlas.com/evidence/qi-2017-chaihu-longgu},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-27. https://www.mecfsatlas.com/evidence/qi-2017-chaihu-longgu
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