Simonyi, Gábor, Bedros, J Róbert, Réthelyi, János et al. · Orvosi hetilap · 2025 · DOI
This paper is a consensus statement from multiple medical experts that reviews what is currently known about ME/CFS, including its varied symptoms affecting the body, thinking, mood, and daily functioning. The authors recognize that ME/CFS is increasingly common but still not well understood or acknowledged in Hungarian medicine, so they compiled international guidelines and treatment suggestions to help healthcare providers better care for patients with this condition.
This consensus statement is important because it brings international ME/CFS expertise to a healthcare system where the condition is underrecognized, potentially improving diagnosis and care for Hungarian patients. By outlining the multidimensional nature of ME/CFS and offering treatment recommendations, it helps bridge the gap between established international understanding and local clinical practice.
This consensus statement does not establish the underlying cause of ME/CFS, nor does it present new experimental or clinical trial data. It does not prove the efficacy of specific treatments, but rather synthesizes and recommends approaches based on existing literature. The authors acknowledge that etiological understanding remains contradictory and incomplete.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Simonyi, Gábor, Bedros, J Róbert, Réthelyi, János, Polgár, Anna, & Kiss, Emese (2025). [Interdisciplinary consensus statement about the diagnosis and treatment of chronic fatigue syndrome/myalgic encephalomyelopathy].. Orvosi hetilap. https://doi.org/10.1556/650.2025.33259
BibTeX
@article{mecfsatlas-simonyi-2025-interdisciplinary-consensus,
author = {Simonyi, Gábor and Bedros, J Róbert and Réthelyi, János and Polgár, Anna and Kiss, Emese},
title = {[Interdisciplinary consensus statement about the diagnosis and treatment of chronic fatigue syndrome/myalgic encephalomyelopathy].},
journal = {Orvosi hetilap},
year = {2025},
doi = {10.1556/650.2025.33259},
note = {PubMed: 40188425},
url = {https://www.mecfsatlas.com/evidence/simonyi-2025-interdisciplinary-consensus},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-26. https://www.mecfsatlas.com/evidence/simonyi-2025-interdisciplinary-consensus
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