Uchiyama-Tanaka, Yoko · Journal of alternative and complementary medicine (New York, N.Y.) · 2018 · DOI
This study tested homeopathic bowel remedies (made from old bacterial samples) in 28 Japanese patients with digestive problems like constipation and diarrhea. About 70% of patients reported some improvement in their symptoms, and no harmful side effects were reported. The researchers suggest these remedies might be a simpler and cheaper option for treating gut-related digestive issues.
Many ME/CFS patients experience gastrointestinal dysbiosis and digestive symptoms that significantly impact quality of life. This study explores whether bowel nosodes might offer a potential therapeutic option for managing these gut-related complications, though rigorous evidence remains limited.
This study does not prove that bowel nosodes are effective treatments, as it lacks a control or placebo group and cannot distinguish treatment effects from natural recovery or placebo response. The small sample size, single-site design, and heterogeneous patient population limit generalizability. Observational improvement ratings are subjective and do not establish causation.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Uchiyama-Tanaka, Yoko (2018). Case Study of Homeopathic Bowel Nosode Remedies for Dysbiotic Japanese Patients.. Journal of alternative and complementary medicine (New York, N.Y.). https://doi.org/10.1089/acm.2017.0061
BibTeX
@article{mecfsatlas-uchiyama-tanaka-2018-case-study,
author = {Uchiyama-Tanaka, Yoko},
title = {Case Study of Homeopathic Bowel Nosode Remedies for Dysbiotic Japanese Patients.},
journal = {Journal of alternative and complementary medicine (New York, N.Y.)},
year = {2018},
doi = {10.1089/acm.2017.0061},
note = {PubMed: 28805460},
url = {https://www.mecfsatlas.com/evidence/uchiyama-tanaka-2018-case-study},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-29. https://www.mecfsatlas.com/evidence/uchiyama-tanaka-2018-case-study
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