E2 ModerateBehavioralPEM not requiredCross-Sectional
Early life stress, negative paternal relationships, and chemical intolerance in middle-aged women: support for a neural sensitization model.
Bell, I R, Baldwin, C M, Russek, L G et al.·Journal of women's health·1998
This study looked at whether women with chemical sensitivity (difficulty tolerating everyday chemicals) had experienced more childhood stress or difficult relationships with their fathers compared to women with depression alone or women without these conditions. The researchers found that women with chemical sensitivity had weaker relationships with their fathers and showed signs of nervous system overactivity. The study suggests that repeated exposure to stress early in life might train the nervous system to react more strongly to chemicals and other triggers.
Autonomic Nervous System