Association of biomarkers with health-related quality of life and history of stressors in myalgic encephalomyelitis/chronic fatigue syndrome patients.
Fenouillet, Emmanuel, Vigouroux, Aude, Steinberg, Jean Guillaume et al.·Journal of translational medicine·2016
This study examined blood markers and muscle function in 36 ME/CFS patients compared to 11 healthy controls to understand whether biological changes relate to symptoms and quality of life. Researchers found three key differences: problems with muscle response to exercise, increased oxidative stress (cellular damage), and changes in immune cells. These biomarkers correlated with how much ME/CFS affected patients' daily lives, especially in those whose illness started after a severe infection.