ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

381–400 of 746 studies

E2 ModerateCohortPEM unclearCross-Sectional

Association of active human herpesvirus-6, -7 and parvovirus b19 infection with clinical outcomes in patients with myalgic encephalomyelitis/chronic fatigue syndrome.

Chapenko, Svetlana, Krumina, Angelika, Logina, Inara et al.·Advances in virology·2012

This study tested 108 ME/CFS patients and 90 healthy people for three viruses: HHV-6, HHV-7, and parvovirus B19. The researchers found that about 65% of ME/CFS patients had active viral infections compared to only 13% of healthy people. Patients with active viral infections showed higher levels of inflammatory markers and experienced more severe symptoms, especially when infected with multiple viruses at once.

Immune SystemPost-Exertional Malaise

E2 ModerateCohortPEM not requiredCase-Control

Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: a case-control study.

Jones, David E J, Hollingsworth, Kieren G, Jakovljevic, Djordje G et al.·European journal of clinical investigation·2012

This study looked at how muscles produce and use energy during exercise in ME/CFS patients compared to healthy people. Researchers found that ME/CFS patients' muscles became more acidic (like buildup of lactic acid) during exercise and took much longer to recover back to normal levels, even after repeated exercise sessions. This abnormal response to exercise may explain why some ME/CFS patients feel worse after exertion rather than better.

Evidence Atlas

Evidence browser

Association of active human herpesvirus-6, -7 and parvovirus b19 infection with clinical outcomes in patients with myalgic encephalomyelitis/chronic fatigue syndrome.

Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: a case-control study.

A natural history study of chronic fatigue syndrome.

Reliability and validity of Short Form 36 Version 2 to measure health perceptions in a sub-group of individuals with fatigue.

Symptom fluctuations and daily physical activity in patients with chronic fatigue syndrome: a case-control study.

Diagnostic accuracy of symptoms characterising chronic fatigue syndrome.

[Chronic fatigue syndrome: study of a consecutive series of 824 cases assessed in two specialized units].

Postinfectious fatigue in adolescents and physical activity.

Nitric oxide metabolite production during exercise in chronic fatigue syndrome: a case-control study.

Exercise tolerance testing in a prospective cohort of adolescents with chronic fatigue syndrome and recovered controls following infectious mononucleosis.

Plasma IL-6, its soluble receptors and F2-isoprostanes at rest and during exercise in chronic fatigue syndrome.

Unravelling the nature of postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: the role of elastase, complement C4a and interleukin-1beta.

Classification of myalgic encephalomyelitis/chronic fatigue syndrome by types of fatigue.

Sleep is not disrupted by exercise in patients with chronic fatigue syndromes.

Abnormalities in pH handling by peripheral muscle and potential regulation by the autonomic nervous system in chronic fatigue syndrome.

Postexertional malaise in women with chronic fatigue syndrome.

Severe versus Moderate criteria for the new pediatric case definition for ME/CFS.

Physiological cost of walking in those with chronic fatigue syndrome (CFS): a case-control study.

Chronic fatigue syndrome combines increased exercise-induced oxidative stress and reduced cytokine and Hsp responses.

The Energy Envelope Theory and myalgic encephalomyelitis/chronic fatigue syndrome.

Curated Collections

Neuroinflammation Evidence

Metabolism & Mitochondria

Biomarkers

PEM-Specific Research