ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

401–420 of 1,186 studies

E2 ModerateCohortPEM unclearCross-Sectional

Evidence for inflammation and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): increased interleukin-1, tumor necrosis factor-α, PMN-elastase, lysozyme and neopterin.

Maes, Michael, Twisk, Frank N M, Kubera, Marta et al.·Journal of affective disorders·2012

This study examined whether people with ME/CFS have higher levels of inflammatory markers—substances in the blood that signal inflammation—compared to healthy people and those with regular fatigue. Researchers found that ME/CFS patients had significantly elevated levels of five different inflammatory markers, and these markers were linked to common ME/CFS symptoms like fatigue, brain fog, and flu-like feelings. The findings suggest that low-grade inflammation in the body may be contributing to ME/CFS symptoms.

Evidence Atlas

Evidence browser

Evidence for inflammation and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): increased interleukin-1, tumor necrosis factor-α, PMN-elastase, lysozyme and neopterin.

Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein-Barr virus IgG antibody titers.

Fibromyalgia and chronic fatigue syndrome in children.

Inflammatory and cell-mediated immune biomarkers in myalgic encephalomyelitis/chronic fatigue syndrome and depression: inflammatory markers are higher in myalgic encephalomyelitis/chronic fatigue syndrome than in depression.

IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression.

Increased IgA and IgM responses against gut commensals in chronic depression: further evidence for increased bacterial translocation or leaky gut.

Association of active human herpesvirus-6, -7 and parvovirus b19 infection with clinical outcomes in patients with myalgic encephalomyelitis/chronic fatigue syndrome.

Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis.

Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controls.

Predictors of Fatigue among Patients with Chronic Fatigue Syndrome.

Activation of cell-mediated immunity in depression: association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression.

Immunophenotyping in post-giardiasis functional gastrointestinal disease and chronic fatigue syndrome.

Stress management skills, neuroimmune processes and fatigue levels in persons with chronic fatigue syndrome.

Heterogeneous nuclear RNPs as targets of autoantibodies in systemic rheumatic diseases.

Humoral and cellular immune responses after influenza vaccination in patients with chronic fatigue syndrome.

Xenotropic murine leukemia virus-related virus-associated chronic fatigue syndrome reveals a distinct inflammatory signature.

Benefit from B-Lymphocyte Depletion Using the Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome

Investigation into the presence of and serological response to XMRV in CFS patients.

An unbiased metagenomic search for infectious agents using monozygotic twins discordant for chronic fatigue.

Detection of antinuclear antibodies by indirect immunofluorescence and by solid phase assay.

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