Detection of antinuclear antibodies by automated indirect immunofluorescence analysis.
Bossuyt, Xavier, Cooreman, Sarah, De Baere, Heidi et al.·Clinica chimica acta; international journal of clinical chemistry·2013
This study tested an automated machine to detect antinuclear antibodies (ANA)—proteins the immune system sometimes makes that can be seen in blood tests. Researchers compared how well this automated system worked compared to traditional methods, using blood samples from people with autoimmune diseases, healthy donors, people with chronic fatigue syndrome, and other patient groups. The machine was good at collecting images but had difficulty identifying the specific patterns of these antibodies accurately.