Aslakson, Eric, Szekely, Smadar, Vernon, Suzanne D et al. · Theoretical biology & medical modelling · 2012 · DOI
Researchers developed a new way to organize and understand patient medical records by translating written descriptions of illness into visual diagrams. They tested this approach using an actual patient interview with someone who was later diagnosed with ME/CFS. This method could help doctors and researchers better track how diseases develop over time and identify important patterns in patient histories.
This study addresses a critical gap in ME/CFS research: the systematic extraction of meaningful information from patient narratives and medical records. Better tools for organizing and understanding disease progression patterns could improve clinical recognition, support research into disease mechanisms, and enable more accurate tracking of how ME/CFS develops over time in individual patients.
This study does not prove the method works reliably across large patient populations or compare its accuracy to other record-organizing systems. It also does not identify actual causes of ME/CFS or validate the approach against established clinical databases. The proof-of-concept is limited to one patient case, so broader effectiveness remains undemonstrated.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Aslakson, Eric, Szekely, Smadar, Vernon, Suzanne D, Bateman, Lucinda, Baumbach, Jan, & Setty, Yaki (2012). Live sequence charts to model medical information.. Theoretical biology & medical modelling. https://doi.org/10.1186/1742-4682-9-22
BibTeX
@article{mecfsatlas-aslakson-2012-live-sequence,
author = {Aslakson, Eric and Szekely, Smadar and Vernon, Suzanne D and Bateman, Lucinda and Baumbach, Jan and Setty, Yaki},
title = {Live sequence charts to model medical information.},
journal = {Theoretical biology & medical modelling},
year = {2012},
doi = {10.1186/1742-4682-9-22},
note = {PubMed: 22703558},
url = {https://www.mecfsatlas.com/evidence/aslakson-2012-live-sequence},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-27. https://www.mecfsatlas.com/evidence/aslakson-2012-live-sequence
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