Bjerregaard, Preben, Nallapaneni, Hari, Gussak, Ihor · Journal of electrocardiology · 2010 · DOI
This review article discusses a heart rhythm pattern called a 'short QT interval' that doctors can see on heart electrical recordings (EKGs). The authors note that while this pattern is rare, it can sometimes be dangerous and increase the risk of sudden cardiac death. They found that short QT intervals have been reported in patients with ME/CFS, along with several other medical conditions, though we still don't fully understand what it means or how to best manage patients who have it.
This study is relevant to ME/CFS because it explicitly identifies shortened QT intervals as an observed cardiac abnormality in ME/CFS patients. Understanding the prevalence and clinical significance of this finding could help clinicians better evaluate cardiac symptoms in ME/CFS and determine whether this represents a meaningful physiological marker or requires specific monitoring.
This review does not establish causation or clinical severity of short QT intervals in ME/CFS; it only documents that the finding has been reported. It does not provide prevalence data specific to ME/CFS populations, nor does it demonstrate that short QT intervals in ME/CFS patients carry the same sudden cardiac death risk as in Short QT Syndrome. The study does not define clear diagnostic criteria or management guidelines applicable to ME/CFS.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Bjerregaard, Preben, Nallapaneni, Hari, & Gussak, Ihor (2010). Short QT interval in clinical practice.. Journal of electrocardiology. https://doi.org/10.1016/j.jelectrocard.2010.06.004
BibTeX
@article{mecfsatlas-bjerregaard-2010-short-interval,
author = {Bjerregaard, Preben and Nallapaneni, Hari and Gussak, Ihor},
title = {Short QT interval in clinical practice.},
journal = {Journal of electrocardiology},
year = {2010},
doi = {10.1016/j.jelectrocard.2010.06.004},
note = {PubMed: 20667544},
url = {https://www.mecfsatlas.com/evidence/bjerregaard-2010-short-interval},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-27. https://www.mecfsatlas.com/evidence/bjerregaard-2010-short-interval
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