Chan, Jessie S M, Ho, Rainbow T H, Wang, Chong-Wen et al. · Evidence-based complementary and alternative medicine : eCAM · 2013 · DOI
This study tested whether qigong—a gentle Chinese exercise and breathing practice—could help people with ME/CFS-like illness feel less tired, anxious, and depressed. Participants either took 10 qigong classes over 5 weeks and then practiced at home, or waited without treatment. The qigong group showed improvements in overall fatigue and depression, but anxiety did not improve significantly.
This study addresses an important unmet need in ME/CFS management by exploring a low-risk complementary therapy for common comorbid symptoms of depression and fatigue. The findings suggest qigong may offer a non-pharmacological option for patients seeking additional symptom management strategies alongside standard care.
This study does not prove qigong is a cure or first-line treatment for ME/CFS, nor does it explain the biological mechanisms underlying any benefits. The term 'CFS-like illness' suggests the cohort may not represent all ME/CFS presentations, and results cannot be assumed to generalize to more severely affected patients or different populations. Short-term improvements do not establish whether benefits persist long-term after intervention cessation.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Chan, Jessie S M, Ho, Rainbow T H, Wang, Chong-Wen, Yuen, Lai Ping, Sham, Jonathan S T, & Chan, Cecilia L W (2013). Effects of qigong exercise on fatigue, anxiety, and depressive symptoms of patients with chronic fatigue syndrome-like illness: a randomized controlled trial.. Evidence-based complementary and alternative medicine : eCAM. https://doi.org/10.1155/2013/485341
BibTeX
@article{mecfsatlas-chan-2013-effects-qigong,
author = {Chan, Jessie S M and Ho, Rainbow T H and Wang, Chong-Wen and Yuen, Lai Ping and Sham, Jonathan S T and Chan, Cecilia L W},
title = {Effects of qigong exercise on fatigue, anxiety, and depressive symptoms of patients with chronic fatigue syndrome-like illness: a randomized controlled trial.},
journal = {Evidence-based complementary and alternative medicine : eCAM},
year = {2013},
doi = {10.1155/2013/485341},
note = {PubMed: 23983785},
url = {https://www.mecfsatlas.com/evidence/chan-2013-effects-qigong},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-29. https://www.mecfsatlas.com/evidence/chan-2013-effects-qigong
Contribute
Private, reviewed by a human. Not a public comment thread.