Chan, Jessie S M, Ho, Rainbow T H, Chung, Ka-Fai et al. · Evidence-based complementary and alternative medicine : eCAM · 2014 · DOI
This study tested whether a gentle movement and breathing practice called Baduanjin Qigong could help people with chronic fatigue syndrome-like illness. Over 9 weeks, 150 participants either took Qigong classes and practiced at home, or waited for treatment. The Qigong group showed improvements in sleep quality, how quickly they fell asleep, fatigue levels, and anxiety and depression symptoms—and the more they practiced, the better they did.
Sleep disturbance and psychological symptoms are major burdens in ME/CFS, and this study provides evidence that a low-cost, accessible behavioral intervention may provide clinically meaningful relief. The dose-response relationship suggests that engagement with the intervention correlates with benefit, which could inform personalized management strategies.
This study does not establish whether Qigong benefits all ME/CFS patients or only those with CFS-like illness (the case definition is not specified in detail). It cannot determine whether improvements are due to the specific mechanics of Qigong, general physical activity, expectation effects, or increased social engagement. The lack of objective measures means we cannot confirm whether fatigue improvements reflect reduced functional limitation or changed perception.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Chan, Jessie S M, Ho, Rainbow T H, Chung, Ka-Fai, Wang, Chong-Wen, Yao, Tzy-Jyun, Ng, Siu-Man, et al. (2014). Qigong exercise alleviates fatigue, anxiety, and depressive symptoms, improves sleep quality, and shortens sleep latency in persons with chronic fatigue syndrome-like illness.. Evidence-based complementary and alternative medicine : eCAM. https://doi.org/10.1155/2014/106048
BibTeX
@article{mecfsatlas-chan-2014-qigong-exercise,
author = {Chan, Jessie S M and Ho, Rainbow T H and Chung, Ka-Fai and Wang, Chong-Wen and Yao, Tzy-Jyun and Ng, Siu-Man and Chan, Cecilia L W},
title = {Qigong exercise alleviates fatigue, anxiety, and depressive symptoms, improves sleep quality, and shortens sleep latency in persons with chronic fatigue syndrome-like illness.},
journal = {Evidence-based complementary and alternative medicine : eCAM},
year = {2014},
doi = {10.1155/2014/106048},
note = {PubMed: 25610473},
url = {https://www.mecfsatlas.com/evidence/chan-2014-qigong-exercise},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-26. https://www.mecfsatlas.com/evidence/chan-2014-qigong-exercise
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