De Venter, Maud, Illegems, Jela, Van Royen, Rita et al. · Comprehensive psychiatry · 2017 · DOI
This study looked at whether different types of childhood trauma are linked to fatigue and physical disability in ME/CFS patients. Researchers found that childhood sexual harassment was strongly associated with worse fatigue and lower physical functioning, while other types of trauma (emotional neglect, emotional abuse, physical threat, and sexual abuse) showed no significant connection. The findings suggest that the specific type of childhood trauma may matter when understanding how trauma relates to ME/CFS symptoms.
Understanding which types of childhood trauma are most strongly linked to ME/CFS symptoms could inform clinical assessment and treatment planning for trauma-informed care in this population. This research highlights the importance of screening for specific trauma subtypes rather than treating all childhood trauma as equivalent in ME/CFS patients.
This cross-sectional study cannot prove that childhood sexual harassment causes ME/CFS or its severity—only that they are associated. The findings do not establish whether trauma triggers ME/CFS development, worsens pre-existing disease, or whether reverse causality or confounding factors explain the relationship. The lack of significant findings for other trauma subtypes does not mean they are unimportant in ME/CFS; negative findings in cross-sectional data may reflect methodological factors rather than true absence of effects.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
De Venter, Maud, Illegems, Jela, Van Royen, Rita, Moorkens, Greta, Sabbe, Bernard G C, & Van Den Eede, Filip (2017). Differential effects of childhood trauma subtypes on fatigue and physical functioning in chronic fatigue syndrome.. Comprehensive psychiatry. https://doi.org/10.1016/j.comppsych.2017.07.006
BibTeX
@article{mecfsatlas-de-venter-2017-differential-effects,
author = {De Venter, Maud and Illegems, Jela and Van Royen, Rita and Moorkens, Greta and Sabbe, Bernard G C and Van Den Eede, Filip},
title = {Differential effects of childhood trauma subtypes on fatigue and physical functioning in chronic fatigue syndrome.},
journal = {Comprehensive psychiatry},
year = {2017},
doi = {10.1016/j.comppsych.2017.07.006},
note = {PubMed: 28806608},
url = {https://www.mecfsatlas.com/evidence/de-venter-2017-differential-effects},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-29. https://www.mecfsatlas.com/evidence/de-venter-2017-differential-effects
Contribute
Private, reviewed by a human. Not a public comment thread.