DiVasta, Amy Desrochers, Alexander, Mark E · Current opinion in pediatrics · 2004 · DOI
This review article explains that fainting is common in teenagers, but most cases are not caused by serious heart problems. Doctors can identify the few teenagers with real heart disease using a detailed patient history, physical examination, and an electrocardiogram (ECG). The article emphasizes that teenagers with certain conditions—including chronic fatigue syndrome, eating disorders, and exercise-related fainting—need extra careful evaluation because their heart problems may be more serious or harder to manage.
For ME/CFS patients, this review is relevant because chronic fatigue syndrome is explicitly identified as a condition requiring particular cardiovascular attention in adolescents and young adults. Syncope and orthostatic symptoms are common in ME/CFS, and this article provides a clinical framework for distinguishing benign from serious cardiac causes, helping guide appropriate referral and testing decisions for ME/CFS patients experiencing fainting or pre-syncope.
This review does not establish the prevalence of syncope or cardiac disease specifically in ME/CFS populations, nor does it provide ME/CFS-specific diagnostic criteria or pathophysiology. It does not prove that syncope in ME/CFS patients has a different underlying mechanism than in other adolescents, and it does not quantify the cardiac risk in ME/CFS compared to other chronic conditions.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
DiVasta, Amy Desrochers & Alexander, Mark E (2004). Fainting freshmen and sinking sophomores: cardiovascular issues of the adolescent.. Current opinion in pediatrics. https://doi.org/10.1097/01.mop.0000133079.40007.62
BibTeX
@article{mecfsatlas-divasta-2004-fainting-freshmen,
author = {DiVasta, Amy Desrochers and Alexander, Mark E},
title = {Fainting freshmen and sinking sophomores: cardiovascular issues of the adolescent.},
journal = {Current opinion in pediatrics},
year = {2004},
doi = {10.1097/01.mop.0000133079.40007.62},
note = {PubMed: 15273492},
url = {https://www.mecfsatlas.com/evidence/divasta-2004-fainting-freshmen},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-30. https://www.mecfsatlas.com/evidence/divasta-2004-fainting-freshmen
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