Hyde, B M · Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada · 1991
This article provides a historical overview of myalgic encephalomyelitis (ME/CFS), tracing how the condition has been understood and documented over time. It examines the disease's recognition in medical literature and explores how ME/CFS has been characterized throughout history. This historical perspective helps patients and the public understand how medical understanding of this illness has evolved.
Historical perspective articles are important for validating ME/CFS as a genuine medical condition with a long clinical record, not a recent or imaginary disease. Understanding how medical professionals have recognized and described ME/CFS over decades helps counter misconceptions and provides context for current research and clinical practice.
This historical review does not establish new clinical evidence, identify disease mechanisms, or demonstrate efficacy of any treatments. Historical documentation does not prove etiology or provide data about prevalence, diagnostic criteria, or pathophysiology—it simply confirms that the condition has been clinically observed and reported.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Hyde, B M (1991). Myalgic encephalomyelitis (chronic fatigue syndrome): an historic perspective.. Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada. https://pubmed.ncbi.nlm.nih.gov/1669354/
BibTeX
@article{mecfsatlas-hyde-1991-myalgic-encephalomyelitis,
author = {Hyde, B M},
title = {Myalgic encephalomyelitis (chronic fatigue syndrome): an historic perspective.},
journal = {Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada},
year = {1991},
note = {PubMed: 1669354},
url = {https://www.mecfsatlas.com/evidence/hyde-1991-myalgic-encephalomyelitis},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-29. https://www.mecfsatlas.com/evidence/hyde-1991-myalgic-encephalomyelitis
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