Karpukhin, I V · Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury · 2001
This study looked at 43 men with erectile dysfunction linked to stress, anxiety, and chronic fatigue. Researchers combined three treatments: a device that uses negative pressure, electric sleep therapy, and a water treatment called Charcot's douche. The combination appeared to help improve sexual function in men whose problems were caused by psychological stress rather than physical causes.
ME/CFS patients frequently experience post-exertional malaise, neurological symptoms, and autonomic dysfunction that can affect sexual function and quality of life. This study suggests that multi-modal physical therapies targeting stress-related sexual dysfunction may warrant investigation in ME/CFS populations, though rigorous modern research is needed.
This study does not establish causation or prove these therapies are specifically effective for ME/CFS-related sexual dysfunction, as ME/CFS was not clearly defined and no control group was included. The small observational design and lack of blinding mean results may reflect placebo effects or natural recovery rather than true treatment efficacy. Cross-cultural and temporal context (2001 Russian literature) limits generalizability.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Karpukhin, I V (2001). [Use of local negative pressure in combination with electric sleep or Charcot's douche for treatment of erectile dysfunctions].. Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury. https://pubmed.ncbi.nlm.nih.gov/11561303/
BibTeX
@article{mecfsatlas-karpukhin-2001-use-local,
author = {Karpukhin, I V},
title = {[Use of local negative pressure in combination with electric sleep or Charcot's douche for treatment of erectile dysfunctions].},
journal = {Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury},
year = {2001},
note = {PubMed: 11561303},
url = {https://www.mecfsatlas.com/evidence/karpukhin-2001-use-local},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-30. https://www.mecfsatlas.com/evidence/karpukhin-2001-use-local
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