Khundadze, M, Mkheidze, R, Geladze, N et al. · Georgian medical news · 2015
This review article examines somatoform disorders—conditions where physical symptoms occur without a clear physical cause—in children and teenagers. It covers several conditions including chronic fatigue syndrome, and discusses why these disorders happen, how they present differently, and how doctors can diagnose and treat them. The authors note that these conditions have become more common over the past 20 years.
This review is relevant to ME/CFS because it positions chronic fatigue syndrome within the broader context of somatoform disorders in pediatric populations and discusses diagnostic criteria and management approaches. Understanding how CFS is classified and differentiated from other conditions that present with fatigue in children can help clarify the condition's distinct biological and clinical features.
This review does not establish causation for any somatoform disorder, nor does it prove whether chronic fatigue syndrome is primarily psychosomatic or organic in nature. As a narrative review rather than a systematic analysis, it cannot quantify the strength of evidence supporting any particular treatment or diagnostic approach, and the abstract does not specify which studies were included or their quality.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
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Primary citation
Khundadze, M, Mkheidze, R, Geladze, N, Bakhtadze, S, & Khachapuridze, N (2015). THE CAUSES AND SYMPTOMS OF SOMATOFORM DISORDERS IN CHILDREN (REVIEW).. Georgian medical news. https://pubmed.ncbi.nlm.nih.gov/26355317/
BibTeX
@article{mecfsatlas-khundadze-2015-causes-symptoms,
author = {Khundadze, M and Mkheidze, R and Geladze, N and Bakhtadze, S and Khachapuridze, N},
title = {THE CAUSES AND SYMPTOMS OF SOMATOFORM DISORDERS IN CHILDREN (REVIEW).},
journal = {Georgian medical news},
year = {2015},
note = {PubMed: 26355317},
url = {https://www.mecfsatlas.com/evidence/khundadze-2015-causes-symptoms},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-30. https://www.mecfsatlas.com/evidence/khundadze-2015-causes-symptoms
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