Kumano-go, Takayuki, Adachi, Hiroyoshi, Sugita, Yoshiro · Nihon rinsho. Japanese journal of clinical medicine · 2007
This study looked at sleep problems in ME/CFS patients using a special laser device to measure blood flow patterns during sleep. The researchers found that different ME/CFS patients showed different types of abnormal sleep patterns, suggesting that ME/CFS may actually be several different conditions rather than one single illness. Sleep disturbances like insomnia, oversleeping, and irregular sleep-wake cycles are common in ME/CFS.
Understanding distinct sleep disturbance subtypes in ME/CFS could help clinicians better characterize patients and tailor treatments. This work supports the growing evidence that ME/CFS may comprise multiple biological subtypes, which could explain why patients respond differently to interventions and why the condition has been so difficult to study.
This study does not prove that sleep disturbances cause ME/CFS or vice versa—it only documents that abnormal sleep patterns exist in affected patients. The study does not establish whether different sleep subtypes correspond to different underlying biological mechanisms or predict treatment outcomes. Additionally, findings from pulse wave analysis may not directly correlate with standard measures of sleep quality or pathology.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Kumano-go, Takayuki, Adachi, Hiroyoshi, & Sugita, Yoshiro (2007). [Sleep disturbance in chronic fatigue syndrome].. Nihon rinsho. Japanese journal of clinical medicine. https://pubmed.ncbi.nlm.nih.gov/17561691/
BibTeX
@article{mecfsatlas-kumano-go-2007-sleep-disturbance,
author = {Kumano-go, Takayuki and Adachi, Hiroyoshi and Sugita, Yoshiro},
title = {[Sleep disturbance in chronic fatigue syndrome].},
journal = {Nihon rinsho. Japanese journal of clinical medicine},
year = {2007},
note = {PubMed: 17561691},
url = {https://www.mecfsatlas.com/evidence/kumano-go-2007-sleep-disturbance},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-30. https://www.mecfsatlas.com/evidence/kumano-go-2007-sleep-disturbance
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