Kusama, Yoshiki, Fukui, Sadahiro, Maruyama, Makiko et al. · Pediatrics international : official journal of the Japan Pediatric Society · 2022 · DOI
This study examines whether ME/CFS can develop in children after they have COVID-19. The researchers reviewed existing information about how post-COVID conditions might lead to ME/CFS symptoms in young patients. This is important because understanding the link between COVID-19 and ME/CFS could help doctors recognize and support children who develop this condition after a viral infection.
Understanding whether COVID-19 can trigger ME/CFS in children is clinically significant for diagnosis and management. Early recognition of post-COVID ME/CFS in pediatric patients may improve outcomes through appropriate medical support and activity management.
This review does not provide new primary data establishing causation between COVID-19 and ME/CFS development. It cannot determine the prevalence or incidence of ME/CFS following COVID-19 in children, nor does it establish whether post-COVID syndrome and ME/CFS are distinct entities or manifestations of the same underlying mechanism.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Kusama, Yoshiki, Fukui, Sadahiro, Maruyama, Makiko, Kamimura, Katsunori, & Maihara, Toshiro (2022). Myalgic encephalomyelitis/chronic fatigue syndrome post coronavirus disease 2019.. Pediatrics international : official journal of the Japan Pediatric Society. https://doi.org/10.1111/ped.14976
BibTeX
@article{mecfsatlas-kusama-2022-myalgic-encephalomyelitis,
author = {Kusama, Yoshiki and Fukui, Sadahiro and Maruyama, Makiko and Kamimura, Katsunori and Maihara, Toshiro},
title = {Myalgic encephalomyelitis/chronic fatigue syndrome post coronavirus disease 2019.},
journal = {Pediatrics international : official journal of the Japan Pediatric Society},
year = {2022},
doi = {10.1111/ped.14976},
note = {PubMed: 35143110},
url = {https://www.mecfsatlas.com/evidence/kusama-2022-myalgic-encephalomyelitis},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-26. https://www.mecfsatlas.com/evidence/kusama-2022-myalgic-encephalomyelitis
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