Larrimore, Christopher, Ramnot, Amanda, Jaghab, Annmarie et al. · The Journal of the American Osteopathic Association · 2019 · DOI
This article reviews what scientists know about ME/CFS, including its symptoms, how it affects the body, and why it's hard to diagnose. The authors discuss both traditional medical approaches and osteopathic treatment (a type of hands-on therapy that focuses on the body's structure and function) as possible ways to help people with ME/CFS feel better. The review emphasizes that ME/CFS is a real, serious illness that deserves more awareness among doctors and better treatment options.
This review addresses the critical diagnostic and therapeutic gaps in ME/CFS care by consolidating existing knowledge and proposing an integrative osteopathic perspective. Increased clinical awareness and expanded treatment approaches could improve outcomes for the millions of patients struggling with delayed diagnoses and limited therapeutic options.
This narrative review does not establish efficacy of osteopathic treatment through randomized controlled trials or quantitative outcome data. It does not prove that osteopathic approaches are superior to or equivalent to standard care, nor does it identify definitive biomarkers or causal mechanisms of ME/CFS pathophysiology.
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Primary citation
Larrimore, Christopher, Ramnot, Amanda, Jaghab, Annmarie, Sarduy, Sofia, Guerrero, George, Troccoli, Peter, et al. (2019). Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Emerging Osteopathic Approach: A Narrative Review.. The Journal of the American Osteopathic Association. https://doi.org/10.7556/jaoa.2019.081
BibTeX
@article{mecfsatlas-larrimore-2019-understanding-myalgic,
author = {Larrimore, Christopher and Ramnot, Amanda and Jaghab, Annmarie and Sarduy, Sofia and Guerrero, George and Troccoli, Peter and Hilton, Kelly and Bested, Alison},
title = {Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Emerging Osteopathic Approach: A Narrative Review.},
journal = {The Journal of the American Osteopathic Association},
year = {2019},
doi = {10.7556/jaoa.2019.081},
note = {PubMed: 31233110},
url = {https://www.mecfsatlas.com/evidence/larrimore-2019-understanding-myalgic},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-26. https://www.mecfsatlas.com/evidence/larrimore-2019-understanding-myalgic
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