Lloyd, Samantha, Chalder, Trudie, Sallis, Hannah M et al. · Behaviour research and therapy · 2012 · DOI
This study tested whether teenagers with chronic fatigue syndrome could benefit from a short telephone-based self-help program based on cognitive-behavioural therapy principles. Sixty-three adolescents received six sessions over three months, with follow-up support. Six months after treatment, participants reported significantly less fatigue and attended school more often, suggesting this simple intervention may help some young people with CFS.
This study provides preliminary evidence that a low-intensity, accessible intervention may reduce fatigue and improve functioning in adolescents with CFS, potentially offering a scalable treatment option. For young people who struggle to access in-person therapy, telephone-based guided self-help represents a pragmatic approach worth further investigation.
The study does not prove that telephone-based guided self-help is superior to standard care or waitlist conditions, as there was no control group. It does not establish whether improvements were due to the specific cognitive-behavioural technique, non-specific therapeutic attention, or natural recovery. Results may not generalise to adolescents with CFS outside specialist clinic settings.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Lloyd, Samantha, Chalder, Trudie, Sallis, Hannah M, & Rimes, Katharine A (2012). Telephone-based guided self-help for adolescents with chronic fatigue syndrome: A non-randomised cohort study.. Behaviour research and therapy. https://doi.org/10.1016/j.brat.2012.02.014
BibTeX
@article{mecfsatlas-lloyd-2012-telephone-based,
author = {Lloyd, Samantha and Chalder, Trudie and Sallis, Hannah M and Rimes, Katharine A},
title = {Telephone-based guided self-help for adolescents with chronic fatigue syndrome: A non-randomised cohort study.},
journal = {Behaviour research and therapy},
year = {2012},
doi = {10.1016/j.brat.2012.02.014},
note = {PubMed: 22459729},
url = {https://www.mecfsatlas.com/evidence/lloyd-2012-telephone-based},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-29. https://www.mecfsatlas.com/evidence/lloyd-2012-telephone-based
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