Mildon, C A · Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada · 1991
This 1991 study documents clinical observations of people with ME/CFS, describing what doctors noticed when examining patients with this condition. The report provides early descriptive information about how the illness presented in patients during that time period. While limited in scope, it contributes to the historical medical record of ME/CFS recognition.
Early clinical observations like this helped establish ME/CFS as a recognizable medical condition worthy of scientific attention. Such descriptive reports from the 1990s provided foundational documentation of patient presentations that informed later diagnostic criteria and research protocols.
This observational report does not establish causation, disease mechanisms, or etiology. It cannot prove the prevalence of specific symptoms, validate diagnostic criteria, or compare ME/CFS to other conditions. Being descriptive rather than analytical, it cannot determine which findings are universal versus individual variations.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Mildon, C A (1991). Clinical observations of chronic fatigue syndrome.. Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada. https://pubmed.ncbi.nlm.nih.gov/1669348/
BibTeX
@article{mecfsatlas-mildon-1991-clinical-observations,
author = {Mildon, C A},
title = {Clinical observations of chronic fatigue syndrome.},
journal = {Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada},
year = {1991},
note = {PubMed: 1669348},
url = {https://www.mecfsatlas.com/evidence/mildon-1991-clinical-observations},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-28. https://www.mecfsatlas.com/evidence/mildon-1991-clinical-observations
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