Murakami, Masato · Nihon rinsho. Japanese journal of clinical medicine · 2007
This review examines how stress and emotional factors play a role in ME/CFS. The authors suggest that treating ME/CFS effectively requires addressing both the body and mind, not just physical symptoms. They discuss how antidepressants and certain herbal medicines may help reduce anxiety and depression, and emphasize that lifestyle changes and behavioral adjustments are important parts of recovery.
This work highlights the importance of addressing psychological and emotional dimensions of ME/CFS alongside physical symptoms. For patients, it validates that stress management and mental health support are legitimate treatment components; for researchers, it emphasizes the need for integrated biopsychosocial models in understanding and treating this complex condition.
This review does not establish causal relationships between psychosocial factors and ME/CFS onset—it only suggests they are involved. It does not provide new clinical trial data proving the efficacy of specific treatments, nor does it identify the underlying biological mechanisms of the disease. The review represents clinical opinion rather than controlled experimental evidence.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Murakami, Masato (2007). [Considerations for the treatment of chronic fatigue syndrome].. Nihon rinsho. Japanese journal of clinical medicine. https://pubmed.ncbi.nlm.nih.gov/17561702/
BibTeX
@article{mecfsatlas-murakami-2007-considerations-treatment,
author = {Murakami, Masato},
title = {[Considerations for the treatment of chronic fatigue syndrome].},
journal = {Nihon rinsho. Japanese journal of clinical medicine},
year = {2007},
note = {PubMed: 17561702},
url = {https://www.mecfsatlas.com/evidence/murakami-2007-considerations-treatment},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-29. https://www.mecfsatlas.com/evidence/murakami-2007-considerations-treatment
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