Wang, Jing-jing, Song, Yu-jing, Wu, Zhong-chao et al. · Zhen ci yan jiu = Acupuncture research · 2009
This review analyzed 28 studies testing whether acupuncture helps people with ME/CFS. Researchers combined results from randomized controlled trials (the gold standard for testing treatments) and found that patients receiving acupuncture reported better outcomes than those in control groups. However, the authors note that more high-quality studies are needed to confirm these findings.
ME/CFS patients experience severe, disabling fatigue with limited effective treatments. This systematic review suggests acupuncture may offer symptomatic benefit, potentially providing an additional therapeutic option. However, high-quality evidence gaps mean clinicians and patients should interpret these results cautiously and seek more rigorous confirmation.
This meta-analysis does not establish the mechanism by which acupuncture might work, nor does it prove acupuncture is superior to other established treatments for CFS. The review includes heterogeneous study designs and quality levels, and many included trials may have used weak diagnostic criteria for CFS; therefore, results may not apply to all CFS populations or clinical contexts. Publication bias and potential inclusion of lower-quality studies cannot be ruled out.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Wang, Jing-jing, Song, Yu-jing, Wu, Zhong-chao, Chu, Xiao-ou, Wang, Xiao-hong, Wang, Xiao-jie, et al. (2009). [A meta analysis on randomized controlled trials of acupuncture treatment of chronic fatigue syndrome].. Zhen ci yan jiu = Acupuncture research. https://pubmed.ncbi.nlm.nih.gov/20209981/
BibTeX
@article{mecfsatlas-wang-2009-meta-analysis,
author = {Wang, Jing-jing and Song, Yu-jing and Wu, Zhong-chao and Chu, Xiao-ou and Wang, Xiao-hong and Wang, Xiao-jie and Wei, Li-na and Wang, Qiao-mei},
title = {[A meta analysis on randomized controlled trials of acupuncture treatment of chronic fatigue syndrome].},
journal = {Zhen ci yan jiu = Acupuncture research},
year = {2009},
note = {PubMed: 20209981},
url = {https://www.mecfsatlas.com/evidence/wang-2009-meta-analysis},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-30. https://www.mecfsatlas.com/evidence/wang-2009-meta-analysis
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