ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

654 studies

601–620 of 654 studies

E0 ConsensusReviewPEM not requiredSystematic-Review

Systematic review of mental health interventions for patients with common somatic symptoms: can research evidence from secondary care be extrapolated to primary care?

Raine, Rosalind, Haines, Andy, Sensky, Tom et al.·BMJ (Clinical research ed.)·2002

Researchers reviewed 61 studies testing mental health treatments for ME/CFS, irritable bowel syndrome, and chronic back pain. They found that cognitive behavioural therapy and behaviour therapy helped with ME/CFS and back pain, while antidepressants helped with irritable bowel syndrome. Treatments worked better when delivered in hospital settings than in GP surgeries, possibly because hospital patients had more severe illness or received closer supervision.

E0 ConsensusReviewPEM unclearEditorial

A status report on chronic fatigue syndrome.

Natelson, Benjamin H, Lange, Gudrun·Environmental health perspectives·2002

This review examines why people develop ME/CFS, a condition marked by extreme tiredness and other symptoms that doctors struggle to explain. The authors suggest that ME/CFS likely isn't caused by a single thing, but rather by several different problems—including brain issues, difficulty handling stress, and concerns about making symptoms worse through activity. They note that while severe infections can trigger ME/CFS, the condition seems to persist through different biological mechanisms than the original infection itself.

Post-Exertional Malaise

E0 ConsensusReviewPEM unclearSystematic-Review

Systematic review of the current literature related to disability and chronic fatigue syndrome.

Ross, S D, Levine, C, Ganz, N et al.·Evidence report/technology assessment (Summary)·2002

This study reviewed all existing research about how ME/CFS affects a person's ability to work and function in daily life. The researchers looked at what scientists had already discovered about disability in ME/CFS to understand the bigger picture of how this illness impacts people. This type of comprehensive review helps identify what we know and what gaps still exist in our understanding.

E0 ConsensusReviewPEM not requiredSystematic-Review

Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications?

Whitehead, William E, Palsson, Olafur, Jones, Kenneth R·Gastroenterology·2002

This review examined how irritable bowel syndrome (IBS) often occurs together with other conditions like fibromyalgia, chronic fatigue syndrome, anxiety, and depression. Researchers found that patients with IBS frequently have multiple other health problems at the same time, suggesting these conditions may share common underlying mechanisms rather than being completely separate disorders.

E0 ConsensusReviewPEM not requiredReview-Narrative

Annotation: Chronic Fatigue Syndrome in children and adolescents.

Garralda, M Elena, Rangel, Luiza·Journal of child psychology and psychiatry, and allied disciplines·2002

This review looked at studies of ME/CFS (chronic fatigue syndrome) in children and teenagers over 20 years. The main symptom is severe tiredness along with other physical symptoms that stop children from doing normal activities. Most cases seem to start after an infection, and many children also have mood problems like depression. Treatment involving family support, gradual increases in activity, and help with mood disorders showed promise, with over two-thirds of children improving.

E0 ConsensusReviewPEM unclearSystematic-Review

Interventions for the treatment and management of chronic fatigue syndrome/myalgic encephalomyelitis.

Bagnall, A M, Whiting, P, Richardson, R et al.·Quality & safety in health care·2002

This review looked at all the available research studies about treatments for ME/CFS to understand which approaches actually work. The authors examined evidence from previously published studies to summarize what we know about managing this condition. This type of review helps doctors and patients understand the current state of treatment options based on the best available evidence.

E0 ConsensusReviewPEM not requiredReview-Narrative

Autonomic nervous system derangement in fibromyalgia syndrome and related disorders.

Cohen, H, Neumann, L, Kotler, M et al.·The Israel Medical Association journal : IMAJ·2001

This review examines how the autonomic nervous system—the part of your nervous system that controls heart rate, breathing, and digestion automatically—may not work properly in fibromyalgia and related conditions like ME/CFS and irritable bowel syndrome. Researchers found evidence that this system dysfunction could have important health consequences, including increased risk of heart problems. However, studies on this topic have produced mixed and sometimes contradictory results.

Autonomic Nervous System

E0 ConsensusReviewPEM not requiredReview-Narrative

Coping and illness cognitions: chronic fatigue syndrome.

Ax, S, Gregg, V H, Jones, D·Clinical psychology review·2001

This study reviews what we know about how people with ME/CFS cope with their illness and how their beliefs about the condition affect their health. The researchers found that how patients think about and manage their illness may play an important role in their physical and mental well-being. The study suggests that understanding these coping strategies could help doctors develop better treatments for ME/CFS.

E0 ConsensusReviewPEM not requiredSystematic-Review

Interventions for the treatment and management of chronic fatigue syndrome: a systematic review.

Whiting, P, Bagnall, A M, Sowden, A J et al.·JAMA·2001

This review looked at 44 studies testing different treatments for ME/CFS to see which ones actually work. The researchers found that cognitive behavioral therapy (talk-based therapy) and graded exercise therapy (gradually increasing activity) showed the most promise, while other treatments like supplements and immunological therapies had unclear or limited benefits. However, the studies used different measurements and methods, making it hard to draw firm conclusions.

Interventions

E0 ConsensusReviewPEM not requiredReview-Narrative

Fibromyalgia and other unexplained clinical conditions.

Aaron, L A, Buchwald, D·Current rheumatology reports·2001

This review examined research comparing fibromyalgia with ME/CFS and other related conditions like irritable bowel syndrome and migraines. The researchers looked at studies that measured how bodies of people with these conditions worked differently, trying to understand what might cause them. The goal was to see whether these conditions share common underlying problems.

E0 ConsensusReviewPEM not requiredReview-Narrative

Neuropsychological functioning in chronic fatigue syndrome: a review.

Michiels, V, Cluydts, R·Acta psychiatrica Scandinavica·2001

This review looked at studies examining thinking and memory problems in ME/CFS patients. Researchers found that people with ME/CFS commonly experience slower thinking speed, difficulty holding information in working memory, and trouble learning new information. The study noted that brain scans haven't shown a consistent pattern that uniquely identifies ME/CFS patients, and that fatigue severity doesn't fully explain the cognitive problems.

Cognitive Impairment

E0 ConsensusReviewPEM not requiredReview-Narrative

Controlled exposures to volatile organic compounds in sensitive groups.

Fiedler, N, Kipen, H M·Annals of the New York Academy of Sciences·2001

This review looked at studies where people with chemical sensitivities were exposed to different odors and chemical mixtures in controlled lab settings. Researchers found that people with chemical sensitivities did have real symptoms when exposed to certain chemicals, even at low levels, but these symptoms weren't always linked to measurable changes in heart rate, breathing, or other body functions that usually indicate stress.

Autonomic Nervous System

E0 ConsensusReviewPEM not requiredReview-Narrative

Chronic fatigue syndrome and fibromyalgia: clinical assessment and treatment.

Friedberg, F, Jason, L A·Journal of clinical psychology·2001

This review examines how ME/CFS and fibromyalgia are similar conditions that doctors don't fully understand yet. The authors looked at research on what causes these illnesses, how to diagnose them (including checking for depression and anxiety), and what treatments work—including medications, alternative therapies, and talking with a therapist. The study suggests that mental health professionals can play an important role in helping patients manage their symptoms.

Diagnostics

E0 ConsensusReviewPEM not requiredReview-Narrative

The neuroendocrinology of chronic fatigue syndrome and fibromyalgia.

Parker, A J, Wessely, S, Cleare, A J·Psychological medicine·2001

This review examined how hormones and brain chemicals differ in ME/CFS patients. Researchers found that some patients have lower stress hormone (cortisol) levels, and their bodies show unusual patterns in serotonin and other brain chemical systems when tested. However, the findings were inconsistent across studies, and it's still unclear whether these changes cause ME/CFS symptoms or result from living with the illness.

Endocrine Disruption

E0 ConsensusReviewPEM unclearSystematic-Review

Defining and managing chronic fatigue syndrome.

Mulrow, C D, Ramirez, G, Cornell, J E et al.·Evidence report/technology assessment (Summary)·2001

This 2001 review examined the medical literature on chronic fatigue syndrome to summarize what was known about how to define and manage the condition. The authors looked at existing research to identify consistent diagnostic criteria and treatment approaches. The goal was to create a clear picture of CFS based on the best available evidence at that time.

Diagnostics

E0 ConsensusReviewPEM not requiredSystematic-Review

[What happens to the fibromyalgia syndrome?].

Maquet, D, Croisier, J L, Crielaard, J M·Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique·2001

This review examined fibromyalgia, a condition causing widespread muscle and joint pain that lasts at least three months. The researchers found that fibromyalgia involves multiple problems working together: abnormal pain processing in the nervous system, poor sleep quality, muscle weakness, and hormonal imbalances. They concluded that treating fibromyalgia effectively requires a team approach addressing all these different issues, not just pain alone.

Pain and Sensitization

E0 ConsensusReviewPEM not requiredSystematic-Review

A review of the evidence for overlap among unexplained clinical conditions.

Aaron, L A, Buchwald, D·Annals of internal medicine·2001

This review examined eight unexplained illnesses—including ME/CFS, fibromyalgia, and irritable bowel syndrome—and found they share many similarities in symptoms (like fatigue and pain), how they affect daily life, and how they respond to laboratory tests. The researchers discovered that many patients have more than one of these conditions at the same time, suggesting they may be related or overlap in important ways.

Diagnostics

E0 ConsensusReviewPEM unclearSystematic-Review

The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders.

Heim, C, Ehlert, U, Hellhammer, D H·Psychoneuroendocrinology·2000

This review examines why some people under chronic stress or after trauma have abnormally low levels of the stress hormone cortisol—a condition called hypocortisolism. The authors found that low cortisol appears in several conditions including ME/CFS, fibromyalgia, and rheumatoid arthritis, not just in PTSD. They propose that persistently low cortisol may make people more vulnerable to developing stress-related illnesses.

Endocrine Disruption

E0 ConsensusReviewPEM unclearReview-Narrative

Chronic fatigue syndrome.

Reid, S, Chalder, T, Cleare, A et al.·BMJ (Clinical research ed.)·2000

This was a systematic review that brought together existing research about chronic fatigue syndrome (ME/CFS) to understand what was known at the time. The researchers looked at multiple studies to summarize the current evidence about the condition. This type of overview helps doctors and patients understand the state of knowledge about ME/CFS.

Interventions

E0 ConsensusReviewPEM not requiredSystematic-Review

Cognitive behaviour therapy for adults with chronic fatigue syndrome.

Price, J R, Couper, J·The Cochrane database of systematic reviews·2000

This review examined whether cognitive behaviour therapy (CBT)—a type of talk therapy that helps people change unhelpful thinking patterns and gradually return to activities—helps adults with ME/CFS. Researchers looked at three high-quality studies and found that CBT did improve physical functioning compared to standard medical care or relaxation therapy. However, the evidence was limited to people who could attend clinic appointments; more research is needed in people with milder or more severe forms of the illness.

Interventions

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Systematic review of mental health interventions for patients with common somatic symptoms: can research evidence from secondary care be extrapolated to primary care?

A status report on chronic fatigue syndrome.

Systematic review of the current literature related to disability and chronic fatigue syndrome.

Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications?

Annotation: Chronic Fatigue Syndrome in children and adolescents.

Interventions for the treatment and management of chronic fatigue syndrome/myalgic encephalomyelitis.

Autonomic nervous system derangement in fibromyalgia syndrome and related disorders.

Coping and illness cognitions: chronic fatigue syndrome.

Interventions for the treatment and management of chronic fatigue syndrome: a systematic review.

Fibromyalgia and other unexplained clinical conditions.

Neuropsychological functioning in chronic fatigue syndrome: a review.

Controlled exposures to volatile organic compounds in sensitive groups.

Chronic fatigue syndrome and fibromyalgia: clinical assessment and treatment.

The neuroendocrinology of chronic fatigue syndrome and fibromyalgia.

Defining and managing chronic fatigue syndrome.

[What happens to the fibromyalgia syndrome?].

A review of the evidence for overlap among unexplained clinical conditions.

The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders.

Chronic fatigue syndrome.

Cognitive behaviour therapy for adults with chronic fatigue syndrome.

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