ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

644 studies

641–644 of 644 studies

E0 ConsensusReviewPEM not requiredReview-Narrative

Serologic and immunologic responses in chronic fatigue syndrome with emphasis on the Epstein-Barr virus.

Jones, J F·Reviews of infectious diseases·1991

This review examined whether ME/CFS is connected to Epstein-Barr virus (EBV), the virus that causes mono. Researchers found that people with ME/CFS had higher levels of antibodies to EBV compared to healthy people, but this doesn't prove the virus causes the disease. They also found that immune cells called natural killer cells—which help fight infections—work differently in ME/CFS patients, though the findings varied between studies.

Immune System

E0 ConsensusReviewPEM unclearReview-Narrative

Post-infectious neuromyasthenia (chronic fatigue syndrome): a summary of ongoing studies.

Salit, I E, Abbey, S E, Moldofsky, H et al.·Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada·1991

This 1991 review examined multiple ongoing studies about ME/CFS (then called post-infectious neuromyasthenia), a condition that causes extreme fatigue and other symptoms following infections. The researchers summarized what different studies were finding about how this illness affects the body and brain. This work helped organize early research efforts to better understand this serious condition.

Post-Exertional Malaise

E0 ConsensusReviewPEM not requiredReview-Narrative

Chronic fatigue syndrome and depression: cause, effect, or covariate.

Abbey, S E, Garfinkel, P E·Reviews of infectious diseases·1991

Many people with ME/CFS experience depression, but it's unclear why. This review examines four possible explanations: depression might be the main illness with fatigue as a symptom, depression might develop because of having ME/CFS, both conditions might occur together separately, or depression might be incorrectly diagnosed. The authors discuss how depression can affect medical tests used to study ME/CFS, which is important to understand when interpreting research results.

Cognitive Impairment

E0 ConsensusReviewPEM unclearEditorial

Postviral fatigue syndrome: time for a new approach.

David, A S, Wessely, S, Pelosi, A J·British medical journal (Clinical research ed.)·1988

This 1988 review examined how ME/CFS was being studied and discussed in medical literature, finding significant problems with how research was being conducted. The authors argued that the condition should not be viewed as simply 'all in your head' or 'purely physical,' but rather as involving multiple factors affecting the body and mind. They called for better research methods and clearer definitions before doctors could effectively help patients.

Diagnostics

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Evidence Atlas

Evidence browser

Serologic and immunologic responses in chronic fatigue syndrome with emphasis on the Epstein-Barr virus.

Post-infectious neuromyasthenia (chronic fatigue syndrome): a summary of ongoing studies.

Chronic fatigue syndrome and depression: cause, effect, or covariate.

Postviral fatigue syndrome: time for a new approach.

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