Resting-state functional connectivity, cognition, and fatigue in response to cognitive exertion: a novel study in adolescents with chronic fatigue syndrome.
Josev, Elisha K, Malpas, Charles B, Seal, Marc L et al.·Brain imaging and behavior·2020
Researchers compared how the brains of teenagers with ME/CFS and healthy teenagers responded to a mentally demanding task using brain imaging. Both groups showed similar changes in brain activity and felt more tired after the mental effort. However, teenagers with ME/CFS started out more fatigued, performed worse on thinking tasks overall, and may have less energy available to draw from when their brain works hard.