A placebo-controlled, double-blind, randomized controlled trial of a natural killer cell stimulant (BioBran MGN-3) in chronic fatigue syndrome.
McDermott, C, Richards, S C M, Thomas, P W et al.·QJM : monthly journal of the Association of Physicians·2006
This study tested whether a supplement called BioBran MGN-3 could reduce fatigue in people with ME/CFS by boosting immune cells called natural killer cells. Seventy-one patients took either the supplement or a placebo for 8 weeks. Both groups improved during the study, but the supplement group did not improve significantly more than the placebo group, suggesting the supplement itself was not the reason for improvement.