ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

261–266 of 266 studies

E3 PreliminaryReviewPEM unclearReview-Narrative

[Chronic fatigue syndrome. Clinical, social psychological problems and management].

Wessely, S·L'Encephale·1994

This review examines ME/CFS by comparing it to an older condition called neurasthenia and explores what causes the illness. The authors suggest that ME/CFS likely involves multiple factors including brain chemistry changes, difficulty perceiving effort, mood problems, and reduced physical activity—rather than being purely psychological or a muscle problem. They recommend cognitive-behavioral therapy (gradual activity increase) and antidepressants as the main treatments, while warning that too much rest can actually make the condition worse long-term.

Sleep

E3 PreliminaryCohortPEM not requiredCase-Control

Consideration of narcolepsy in the differential diagnosis of chronic fatigue syndrome.

Ambrogetti, A, Olson, L G·The Medical journal of Australia·1994

This study describes four patients who were initially diagnosed with chronic fatigue syndrome (CFS) but actually had a different condition called narcolepsy, which causes extreme daytime sleepiness. When these patients were properly diagnosed with narcolepsy and treated with a medication called methylphenidate, their symptoms improved significantly or resolved completely. The authors suggest that doctors should carefully check for narcolepsy in patients with CFS who report severe daytime sleepiness.

Sleep

E3 PreliminaryReviewPEM not requiredReview-Narrative

[Chronic fatigue syndrome].

Sternon, J, Decaux, G, Hoffmann, G·Revue medicale de Bruxelles·1994

This paper describes how doctors can diagnose ME/CFS using specific criteria and discusses what might cause the condition. The authors note that viral infections may trigger ME/CFS, and that anxiety or depression can make symptoms worse. Importantly, they found that some patients improve on their own after a few years, though most don't respond well to available treatments.

DiagnosticsSleep

E3 PreliminaryReviewPEM not requiredReview-Narrative

Pharmacological approaches to the therapy of chronic fatigue syndrome.

McCluskey, D R·Ciba Foundation symposium·1993

This study examined various medications used to treat ME/CFS and found that none completely resolved symptoms. The researchers suggest that ME/CFS may be caused by a sleep regulation problem in the brain, which leads to not only extreme tiredness but also pain sensitivity, temperature control issues, and mood problems. They propose that medications affecting brain chemicals, especially serotonin, might help and should be tested in larger clinical trials.

Sleep

E3 PreliminaryReviewPEM unclearReview-Narrative

[Neuro-psychiatric aspects of chronic fatigue syndrome].

Shimizu, T·Nihon rinsho. Japanese journal of clinical medicine·1992

This review examines the differences between ME/CFS and other conditions that can look similar, particularly fibromyalgia and depression. The authors explain that ME/CFS is not a psychological disorder and that sleep disturbances may play a central role in the condition. They suggest that brain imaging technology could help doctors more accurately identify ME/CFS in the future.

Sleep

E3 PreliminaryCommentaryPEM unclearEditorial

Fibromyalgia, chronic fatigue syndrome, and myofascial pain syndrome.

Goldenberg, D L·Current opinion in rheumatology·1991

This 1991 editorial reviews emerging research on fibromyalgia, chronic fatigue syndrome, and myofascial pain, observing that these conditions often overlap and may share common features related to pain perception, hormones, and muscle function. The authors note that early studies investigating these underlying mechanisms showed promise, though therapeutic trials at the time were not particularly encouraging. These are preliminary early findings, and the overlaps described may not directly apply to ME/CFS.

Pain and SensitizationSleepDiagnostics

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[Chronic fatigue syndrome. Clinical, social psychological problems and management].

Consideration of narcolepsy in the differential diagnosis of chronic fatigue syndrome.

[Chronic fatigue syndrome].

Pharmacological approaches to the therapy of chronic fatigue syndrome.

[Neuro-psychiatric aspects of chronic fatigue syndrome].

Fibromyalgia, chronic fatigue syndrome, and myofascial pain syndrome.

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