A metagenomic approach to investigate the microbial causes of myalgic encephalomyelitis/chronic fatigue syndrome: moving beyond XMRV.
Miller, Ruth R, Gardy, Jennifer L, Tang, Patrick et al.·Fatigue : biomedicine, health & behavior·2013
This study used advanced genetic sequencing techniques to search for microorganisms (bacteria, viruses, and fungi) that might cause ME/CFS. Rather than looking for one specific virus, the researchers cast a wider net to detect any microbes present in patient samples. This approach moved beyond previous unsuccessful searches for a single virus, offering a more comprehensive way to understand whether infections play a role in ME/CFS.