ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

41–46 of 46 studies

E3 PreliminaryPEM not requiredPreliminaryCase-ControlEditor reviewed

New Clinical Phenotype of the Post-Covid Syndrome: Fibromyalgia and Joint Hypermobility Condition.

Gavrilova, Natalia, Soprun, Lidiia, Lukashenko, Maria et al.·Pathophysiology : the official journal of the International Society for Pathophysiology·2022

This study describes a pattern found in some people who developed fibromyalgia (widespread pain) after COVID-19 infection. The researchers noticed that young women with loose, flexible joints who had COVID-19 and a specific tendon injury were more likely to develop fibromyalgia along with signs of inflammation. The study presents three patient cases that fit this pattern, suggesting COVID-19 may trigger fibromyalgia in people whose connective tissues are already prone to damage.

Immune SystemLong COVID Overlap

E3 PreliminaryPEM unclearPreliminaryEditor reviewed

Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome.

Komaroff, Anthony L, Lipkin, W Ian·Trends in molecular medicine·2021

This article compares myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) with long COVID to see if they might share similar causes. The authors suggest that some people who develop long COVID symptoms—like persistent fatigue, cognitive problems, and pain—may experience similar biological problems to those seen in ME/CFS. Understanding these shared mechanisms could help doctors better treat both conditions.

Energy MetabolismLong COVID Overlap

E2 ModeratePEM not requiredModerate confidenceCross-SectionalMachine-drafted

Lowered oxygen saturation and increased body temperature in acute COVID-19 largely predict chronic fatigue syndrome and affective symptoms due to Long COVID: A precision nomothetic approach.

Al-Hadrawi, Dhurgham Shihab, Al-Rubaye, Haneen Tahseen, Almulla, Abbas F et al.·Acta neuropsychiatrica·2023

This study examined whether low oxygen levels and high fever during acute COVID-19 could predict who develops Long COVID symptoms like fatigue, depression, and anxiety. Researchers found that these two early warning signs, combined with being female, could explain about 61% of why some people develop these lingering symptoms. They also identified a subgroup (about 27% of Long COVID patients) with particularly severe oxygen drops and fever who experienced the worst combination of fatigue, mood problems, and digestive symptoms.

Long COVID Overlap

E3 PreliminaryPEM unclearPreliminaryReview-NarrativeMachine-drafted

Fatigue in Post-Acute Sequelae of Coronavirus Disease 2019.

Abbott, Zachary, Summers, William, Niehaus, William·Physical medicine and rehabilitation clinics of North America·2023

This review examines fatigue experienced by people recovering from COVID-19, which can be severe and long-lasting. The authors explain that this fatigue likely has multiple different causes in different people, rather than one single explanation. They suggest that treatments work best when doctors identify what might be causing each patient's fatigue and create personalized activity plans that gradually increase over time.

Long COVID Overlap

E3 PreliminaryPEM unclearPreliminaryGuidelineMachine-drafted

Postacute Sequelae of SARS-CoV-2 Infection-Lessons Learned From a Coordinated Health System Response.

Ganesh, Ravindra, Vanichkachorn, Greg S, Munipalli, Bala et al.·Mayo Clinic proceedings. Innovations, quality & outcomes·2022

This study describes how Mayo Clinic, a large healthcare system across five states, created a coordinated plan to help patients recover from long-term COVID-19 symptoms. Doctors from many different specialties worked together to develop consistent guidelines for evaluating and treating these patients. The system includes specialized appointment forms, sample collection for research, and dedicated treatment programs to provide better care.

Long COVID Overlap

E3 PreliminaryPEM unclearPreliminaryMachine-drafted

Myalgic encephalomyelitis/chronic fatigue syndrome post coronavirus disease 2019.

Kusama, Yoshiki, Fukui, Sadahiro, Maruyama, Makiko et al.·Pediatrics international : official journal of the Japan Pediatric Society·2022

This study examines whether ME/CFS can develop in children after they have COVID-19. The researchers reviewed existing information about how post-COVID conditions might lead to ME/CFS symptoms in young patients. This is important because understanding the link between COVID-19 and ME/CFS could help doctors recognize and support children who develop this condition after a viral infection.

Long COVID Overlap

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New Clinical Phenotype of the Post-Covid Syndrome: Fibromyalgia and Joint Hypermobility Condition.

Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome.

Lowered oxygen saturation and increased body temperature in acute COVID-19 largely predict chronic fatigue syndrome and affective symptoms due to Long COVID: A precision nomothetic approach.

Fatigue in Post-Acute Sequelae of Coronavirus Disease 2019.

Postacute Sequelae of SARS-CoV-2 Infection-Lessons Learned From a Coordinated Health System Response.

Myalgic encephalomyelitis/chronic fatigue syndrome post coronavirus disease 2019.

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