Reduced Endothelial Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-Results From Open-Label Cyclophosphamide Intervention Study.
Sørland, Kari, Sandvik, Miriam Kristine, Rekeland, Ingrid Gurvin et al.·Frontiers in medicine·2021
This study found that blood vessels in people with ME/CFS don't work as well as they do in healthy people. The researchers measured how blood vessels widen and respond to changes in blood flow, and found these responses were reduced in ME/CFS patients. Interestingly, when patients received a strong immune-suppressing drug called cyclophosphamide, improvements in symptoms didn't match up with improvements in blood vessel function.