Main neuroendocrine features, diagnosis and therapeutic possibilities in the chronic fatigue syndrome, an underdiagnosed entity.
Amihăesei, Ioana Cristina, Cojocaru, Elena·Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2014
ME/CFS is a serious illness marked by extreme tiredness that doesn't improve with rest, along with problems concentrating, pain, and worsening symptoms after activity. Diagnosis requires at least six months of severe fatigue plus four or more other specific symptoms. Current treatments focus on behavioral approaches and pacing rather than medications, though only about 5% of people fully recover, and more than half become unable to work.