ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

741–760 of 6,187 studies

E1 ReplicatedCohortPEM requiredObservational

Cardiopulmonary exercise testing and post-exertional malaise in ME/CFS: A retrospective analysis

Staci R. Stevens, Christopher R. Snell, Jared N. Stevens et al.·Journal of Translational Medicine·2018·n=51

ME/CFS patients underwent two consecutive days of cardiopulmonary exercise testing (CPET). On the second day, patients showed significantly reduced VO2 max and anaerobic threshold compared to the first day — and compared to healthy and disease controls who recovered normally. This objective impairment matches the subjective PEM experience.

DiagnosticsPost-Exertional Malaise

E1 ReplicatedTrialPEM unclearCase-Control

Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment.

Roerink, Megan E, Knoop, Hans, Bronkhorst, Ewald M et al.·Journal of translational medicine·2017

Researchers compared immune signaling molecules (cytokines) in the blood of 50 women with ME/CFS to 48 healthy women and found two markers were elevated in the ME/CFS group: IL-12p40 and CSF-1. They also tested whether a drug called anakinra (which blocks inflammation) could help reduce these markers, but found it did not significantly change cytokine levels after 4 weeks of treatment.

Evidence Atlas

Evidence browser

Cardiopulmonary exercise testing and post-exertional malaise in ME/CFS: A retrospective analysis

Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment.

Guided graded exercise self-help plus specialist medical care versus specialist medical care alone for chronic fatigue syndrome (GETSET): a pragmatic randomised controlled trial.

Cytokine signature associated with disease severity in chronic fatigue syndrome patients

Kinesiophobia and maladaptive coping strategies prevent improvements in pain catastrophizing following pain neuroscience education in fibromyalgia/chronic fatigue syndrome: An explorative study.

Cost-Utility of Home-Based Fatigue Self-Management versus Usual Care for the Treatment of Chronic Fatigue Syndrome.

[Pharmacological treatment of patients with chronic fatigue syndrome].

[Chaihu Longgu Muli decoction combined with acupuncture at back-shu points for chronic fatigue syndrome].

[Efficacy of acupoint catgut embedding combined with ginger-partitioned moxibustion on chronic fatigue syndrome of spleen-kidney yang deficiency syndrome and its effects on T lymphocyte subsets and activity of NK cell].

Muscle injections with lidocaine improve resting fatigue and pain in patients with chronic fatigue syndrome.

Long-term economic evaluation of cognitive-behavioural group treatment versus enhanced usual care for functional somatic syndromes.

[Chronic fatigue syndrome treated with transcutaneous electrical acupoint stimulation: a randomized controlled trial].

Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial.

Guided graded exercise self-help as a treatment of fatigue in chronic fatigue syndrome.

Chronic fatigue syndrome treated by the traditional Chinese procedure abdominal tuina: a randomized controlled clinical trial.

Effectiveness of a group-based self-management program for people with chronic fatigue syndrome: a randomized controlled trial.

Adiponectin Potentially Contributes to the Antidepressive Effects of Baduanjin Qigong Exercise in Women With Chronic Fatigue Syndrome-Like Illness.

Economic evaluation of multidisciplinary rehabilitation treatment versus cognitive behavioural therapy for patients with chronic fatigue syndrome: A randomized controlled trial.

Intermittent and graded exercise effects on NK cell degranulation markers LAMP-1/LAMP-2 and CD8+CD38+ in chronic fatigue syndrome/myalgic encephalomyelitis.

Heart rate variability biofeedback therapy and graded exercise training in management of chronic fatigue syndrome: An exploratory pilot study.

Curated Collections

Neuroinflammation Evidence

Metabolism & Mitochondria

Biomarkers

PEM-Specific Research