Levels of DHEA and DHEAS and responses to CRH stimulation and hydrocortisone treatment in chronic fatigue syndrome.
Cleare, A J, O'Keane, V, Miell, J P·Psychoneuroendocrinology·2004
This study looked at stress hormone levels in people with ME/CFS, specifically a hormone called DHEA that affects mood, memory, and sleep. Researchers compared 16 ME/CFS patients to 16 healthy controls and tested how their bodies responded to a hormone challenge. They also gave some patients a low-dose steroid medication for a month to see if it helped. The findings suggest that DHEA levels are higher in ME/CFS and may relate to how disabled patients feel, and that low-dose steroid treatment can lower these levels and improve symptoms in some patients.