ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

921–940 of 6,187 studies

Treatment with staphylococcus toxoid in fibromyalgia/chronic fatigue syndrome--a randomised controlled trial.

Zachrisson, Olof, Regland, Björn, Jahreskog, Marianne et al.·European journal of pain (London, England)·2002

Researchers tested whether injections of a substance called staphylococcus toxoid could help people with fibromyalgia and chronic fatigue syndrome (ME/CFS). Over 6 months, 100 patients received either the active treatment or placebo injections. Two-thirds of patients receiving the active treatment reported improvement compared to only one-fifth receiving placebo, suggesting the treatment may help some people with these conditions.

Immune System

E1 ReplicatedTrialPEM not requiredMechanistic

Neuropsychological performance and noradrenaline function in chronic fatigue syndrome under conditions of high arousal.

Morriss, Richard K, Robson, Michael J, Deakin, J F William·Psychopharmacology·2002

This study tested whether people with ME/CFS have unusually sensitive brain receptors that respond to a hormone-like drug called clonidine. Researchers gave 10 ME/CFS patients and 10 healthy controls either clonidine or a placebo while they performed stressful thinking tasks, and measured their hormones, blood pressure, and thinking speed. ME/CFS patients showed slightly stronger hormone responses to clonidine and were faster at starting a planning task, suggesting their brains may react more strongly to stress-related chemical signals.

Evidence Atlas

Evidence browser

Treatment with staphylococcus toxoid in fibromyalgia/chronic fatigue syndrome--a randomised controlled trial.

Neuropsychological performance and noradrenaline function in chronic fatigue syndrome under conditions of high arousal.

Predictors of response to treatment for chronic fatigue syndrome.

Short-term group therapy for patients with chronic fatigue syndrome.

Cognitive behaviour therapy for chronic fatigue syndrome: a multicentre randomised controlled trial.

Hypothalamo-pituitary-adrenal axis dysfunction in chronic fatigue syndrome, and the effects of low-dose hydrocortisone therapy.

Randomised controlled trial of patient education to encourage graded exercise in chronic fatigue syndrome.

Fludrocortisone acetate to treat neurally mediated hypotension in chronic fatigue syndrome: a randomized controlled trial.

Long-term outcome of cognitive behavior therapy versus relaxation therapy for chronic fatigue syndrome: a 5-year follow-up study.

Plasma leptin in chronic fatigue syndrome and a placebo-controlled study of the effects of low-dose hydrocortisone on leptin secretion.

Chronic fatigue in general practice: is counselling as good as cognitive behaviour therapy? A UK randomised trial.

A small, randomized, placebo-controlled trial of the use of antiviral therapy for patients with chronic fatigue syndrome.

A randomized, double-blind placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome.

Decreased bone mineral density during low dose glucocorticoid administration in a randomized, placebo controlled trial.

Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome.

Low-dose hydrocortisone in chronic fatigue syndrome: a randomised crossover trial.

Lymphocyte markers and natural killer cell activity in fibromyalgia syndrome: effects of low-dose, sublingual use of human interferon-alpha.

Low-dose hydrocortisone for treatment of chronic fatigue syndrome: a randomized controlled trial.

Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome.

Effects of staphylococcus toxoid vaccine on pain and fatigue in patients with fibromyalgia/chronic fatigue syndrome.

Curated Collections

Neuroinflammation Evidence

Metabolism & Mitochondria

Biomarkers

PEM-Specific Research