ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

921–940 of 6,157 studies

E1 ReplicatedTrialPEM not requiredLongitudinal

Long-term outcome of cognitive behavior therapy versus relaxation therapy for chronic fatigue syndrome: a 5-year follow-up study.

Deale, A, Husain, K, Chalder, T et al.·The American journal of psychiatry·2001

Researchers compared two types of therapy for ME/CFS: cognitive behavior therapy (CBT, which focuses on changing thought patterns and gradually increasing activity) and relaxation therapy. After 5 years, 68% of people who received CBT reported feeling much or very much improved, compared to 36% who received relaxation therapy. However, neither therapy fully eliminated fatigue symptoms, and some patients found it hard to keep improving after their regular treatment ended.

Evidence Atlas

Evidence browser

Long-term outcome of cognitive behavior therapy versus relaxation therapy for chronic fatigue syndrome: a 5-year follow-up study.

Plasma leptin in chronic fatigue syndrome and a placebo-controlled study of the effects of low-dose hydrocortisone on leptin secretion.

Chronic fatigue in general practice: is counselling as good as cognitive behaviour therapy? A UK randomised trial.

A small, randomized, placebo-controlled trial of the use of antiviral therapy for patients with chronic fatigue syndrome.

A randomized, double-blind placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome.

Decreased bone mineral density during low dose glucocorticoid administration in a randomized, placebo controlled trial.

Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome.

Low-dose hydrocortisone in chronic fatigue syndrome: a randomised crossover trial.

Lymphocyte markers and natural killer cell activity in fibromyalgia syndrome: effects of low-dose, sublingual use of human interferon-alpha.

Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome.

Low-dose hydrocortisone for treatment of chronic fatigue syndrome: a randomized controlled trial.

Effects of staphylococcus toxoid vaccine on pain and fatigue in patients with fibromyalgia/chronic fatigue syndrome.

A preliminary placebo-controlled crossover trial of fludrocortisone for chronic fatigue syndrome.

Effect of growth hormone treatment in patients with chronic fatigue syndrome: a preliminary study.

Single-blind, placebo phase-in trial of two escalating doses of selegiline in the chronic fatigue syndrome.

Illness beliefs and treatment outcome in chronic fatigue syndrome.

Consequences of live poliovirus vaccine administration in chronic fatigue syndrome.

Clinical improvement in chronic fatigue syndrome is not associated with lymphocyte subsets of function or activation.

Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome.

Intravenous immunoglobulin is ineffective in the treatment of patients with chronic fatigue syndrome.

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