Xue, Kai-Yang, Quan, Fei, Tang, Jia-Xuan et al. · Zhongguo zhen jiu = Chinese acupuncture & moxibustion · 2023 · DOI
This study tested whether a traditional Chinese medicine treatment called bamboo-based medicinal moxibustion could help people with chronic fatigue syndrome. Sixty-four patients received either this moxibustion treatment or standard acupuncture over two 6-day courses. The moxibustion group showed greater improvements in fatigue and mood symptoms, and had better immune system markers (T lymphocytes) compared to acupuncture.
This study provides preliminary evidence that moxibustion may address both symptomatic fatigue and potential immune dysregulation in ME/CFS, particularly T cell subset abnormalities. Understanding non-pharmacological interventions that modulate immune markers could offer patients additional therapeutic options, though larger, rigorously controlled studies are needed.
This study does not establish that moxibustion is superior to standard care or placebo, as there was no sham-control arm and blinding status is unclear. The observed changes in T lymphocyte markers are correlational; causality cannot be inferred, and whether these immune changes produce clinical benefit remains unproven. Results may not generalize to ME/CFS populations outside China or to different disease severity levels.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
The first block is for the primary paper and is the citation you should use in research work. The atlas-snapshot line only applies if you are specifically referring to this atlas’s reading of the paper on the date shown.
Primary citation
Xue, Kai-Yang, Quan, Fei, Tang, Jia-Xuan, Xiao, Cai-Hong, Lu, Chun-Xia, & Cui, Jin (2023). [Bamboo-based medicinal moxibustion for chronic fatigue syndrome: a randomized controlled trial].. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. https://doi.org/10.13703/j.0255-2930.20220818-k0001
BibTeX
@article{mecfsatlas-xue-2023-bamboo-based,
author = {Xue, Kai-Yang and Quan, Fei and Tang, Jia-Xuan and Xiao, Cai-Hong and Lu, Chun-Xia and Cui, Jin},
title = {[Bamboo-based medicinal moxibustion for chronic fatigue syndrome: a randomized controlled trial].},
journal = {Zhongguo zhen jiu = Chinese acupuncture & moxibustion},
year = {2023},
doi = {10.13703/j.0255-2930.20220818-k0001},
note = {PubMed: 37161800},
url = {https://www.mecfsatlas.com/evidence/xue-2023-bamboo-based},
}Atlas snapshot reference
ME/CFS Atlas. Generator v1 / Scanner v1.4 / policy v0.1. Accessed 2026-05-30. https://www.mecfsatlas.com/evidence/xue-2023-bamboo-based
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