ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

320 studies

281–300 of 320 studies

Hypothalamo-pituitary-adrenal axis dysfunction in chronic fatigue syndrome, and the effects of low-dose hydrocortisone therapy.

Cleare, A J, Miell, J, Heap, E et al.·The Journal of clinical endocrinology and metabolism·2001

This study examined whether ME/CFS patients have problems with their stress hormone system (called the HPA axis) and whether a low dose of the steroid hormone hydrocortisone could help. Researchers found that ME/CFS patients had lower levels of cortisol (a stress hormone) in their urine and a reduced response to certain hormone challenges, suggesting their adrenal glands may not be producing enough cortisol. When some patients received hydrocortisone treatment, their fatigue improved and their hormone responses normalized.

Evidence Atlas

Evidence browser

Hypothalamo-pituitary-adrenal axis dysfunction in chronic fatigue syndrome, and the effects of low-dose hydrocortisone therapy.

Randomised controlled trial of patient education to encourage graded exercise in chronic fatigue syndrome.

Cognitive behaviour therapy for chronic fatigue syndrome: a multicentre randomised controlled trial.

Decreased bone mineral density during low dose glucocorticoid administration in a randomized, placebo controlled trial.

A randomized, double-blind placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome.

Lymphocyte markers and natural killer cell activity in fibromyalgia syndrome: effects of low-dose, sublingual use of human interferon-alpha.

Low-dose hydrocortisone in chronic fatigue syndrome: a randomised crossover trial.

Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome.

Illness beliefs and treatment outcome in chronic fatigue syndrome.

Effects of staphylococcus toxoid vaccine on pain and fatigue in patients with fibromyalgia/chronic fatigue syndrome.

Effect of growth hormone treatment in patients with chronic fatigue syndrome: a preliminary study.

A preliminary placebo-controlled crossover trial of fludrocortisone for chronic fatigue syndrome.

Single-blind, placebo phase-in trial of two escalating doses of selegiline in the chronic fatigue syndrome.

Low-dose hydrocortisone for treatment of chronic fatigue syndrome: a randomized controlled trial.

Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome.

Consequences of live poliovirus vaccine administration in chronic fatigue syndrome.

Randomised controlled trial of graded exercise in patients with the chronic fatigue syndrome.

Intravenous immunoglobulin is ineffective in the treatment of patients with chronic fatigue syndrome.

Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome.

Clinical improvement in chronic fatigue syndrome is not associated with lymphocyte subsets of function or activation.

Curated Collections

Neuroinflammation Evidence

Metabolism & Mitochondria

Biomarkers

PEM-Specific Research