ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

2423 studies

1521–1540 of 2,423 studies

[Chronic fatigue syndrome in a 15-year-old girl].

Díaz-Caneja Greciano, A, Rodríguez Sosa, J T, Aguilera Albesa, S et al.·Anales de pediatria (Barcelona, Spain : 2003)·2007

This report describes a 15-year-old girl diagnosed with ME/CFS (chronic fatigue syndrome), a condition that causes severe tiredness and lack of energy without an obvious physical cause. The doctors emphasize that ME/CFS should be considered when young people have chronic fatigue along with other symptoms but medical tests don't reveal why. Treatment focused on rehabilitation with cognitive behavioral therapy (talking therapy to address thoughts and behaviors) combined with a gradual, structured increase in activity levels.

Diagnostics

E3 PreliminaryReviewPEM unclearReview-Narrative

Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndrome.

Meeus, Mira, Nijs, Jo·Clinical rheumatology·2007

Many people with ME/CFS experience widespread pain in addition to fatigue, similar to fibromyalgia. This paper proposes that both conditions may be caused by 'central sensitization'—a problem where the nervous system becomes overly sensitive to pain signals. The authors review evidence suggesting this mechanism could explain ME/CFS pain, though more research is needed to confirm it.

Pain and Sensitization

E3 PreliminaryCommentaryPEM not requiredEditorial

Drug residues store in the body following cessation of use: impacts on neuroendocrine balance and behavior--use of the Hubbard sauna regimen to remove toxins and restore health.

Cecchini, Marie, LoPresti, Vincent·Medical hypotheses·2007

This paper proposes that medications and drugs can accumulate in body fat over time and potentially cause long-term health problems even after someone stops taking them. The authors suggest that a treatment program involving exercise, sauna use, and vitamins might help remove these stored substances from the body and improve symptoms in conditions like ME/CFS.

Endocrine Disruption

E3 PreliminaryReviewPEM unclearReview-Narrative

Myalgic encephalomyelitis: a review with emphasis on key findings in biomedical research.

Hooper, M·Journal of clinical pathology·2007

This review examines what scientific research has discovered about ME/CFS, a complex illness that affects multiple body systems and causes long-lasting tiredness, pain, and other symptoms. The authors discuss not only the medical findings but also how disagreements and differing opinions among doctors and scientists have affected research and care for ME/CFS patients. They emphasize that these broader debates have real consequences for patients seeking answers and proper treatment.

Diagnostics

E3 PreliminaryReviewPEM not requiredReview-Narrative

[Overview of psychiatric therapy for chronic fatigue syndrome].

Yamadera, Wataru, Itoh, Hiroshi·Nihon rinsho. Japanese journal of clinical medicine·2007

This review examines how talking therapies, particularly cognitive behavioral therapy (CBT), can help people with ME/CFS. CBT focuses on identifying unhelpful thinking patterns and behaviors—like perfectionism, avoidance, and constantly searching for physical causes—that may be making fatigue worse. The approach involves keeping steady activity levels and making small, planned increases over time, rather than pushing hard and then collapsing.

E3 PreliminaryBehavioralPEM not requiredObservational

Orthostatic panic attacks among Vietnamese refugees.

Hinton, Devon E, Hinton, Ladson, Tran, Minh et al.·Transcultural psychiatry·2007

This study looked at Vietnamese refugees who experienced panic attacks triggered by standing up quickly from a sitting or lying position (orthostatic dizziness). The researchers found that these panic attacks were common among this group and were often linked to trauma memories and cultural beliefs about health. The study suggests that doctors treating Vietnamese refugees should check for and treat these specific panic attacks as part of their care.

Autonomic Nervous System

E3 PreliminaryReviewPEM not requiredReview-Narrative

[Clinical features of chronic fatigue syndrome--symptoms].

Ban, Nobutaro, Saiki, Takuya, Ko, Gyoshin et al.·Nihon rinsho. Japanese journal of clinical medicine·2007

This review article summarizes the most common symptoms experienced by people with ME/CFS. The researchers identified and described the top 10 symptoms in detail, including severe fatigue, problems with memory and concentration, muscle pain, poor sleep, and headaches. Understanding these symptom patterns can help doctors recognize and diagnose ME/CFS more accurately.

Pain and SensitizationCognitive Impairment

E3 PreliminaryCohortPEM not requiredCase-Control

Successful use of a primary care practice-specialty collaboration in the care of an adolescent with chronic fatigue syndrome.

Kuo, Dennis Z, Cheng, Tina L, Rowe, Peter C·Pediatrics·2007

This case report describes how one teenager with ME/CFS improved significantly when their regular doctor and a specialized ME/CFS expert worked together as a team, even though they lived in different cities. By staying in regular contact through phone calls and emails and clearly dividing responsibilities, the two doctors were able to manage the teen's symptoms more effectively. The study suggests that this type of teamwork between primary care doctors and specialists can help young people with ME/CFS get better care.

Interventions

E3 PreliminaryDiagnosticPEM not requiredMethods-Paper

The chronic fatigue syndrome: a comparative pathway analysis.

Emmert-Streib, Frank·Journal of computational biology : a journal of computational molecular cell biology·2007

This study developed a new method to find biological pathways that go wrong in ME/CFS, rather than just looking at individual genes. The researchers compared how biological systems work differently in sick versus healthy people using computer analysis of gene expression data. This approach helps scientists understand ME/CFS as a disease of interconnected biological processes.

E3 PreliminaryReviewPEM not requiredReview-Narrative

[Autonomic function and child chronic fatigue syndrome].

Tanaka, Hidetaka·Nihon rinsho. Japanese journal of clinical medicine·2007

This review examined how the autonomic nervous system—the part of your nervous system that controls automatic functions like heart rate and blood pressure—might be involved in childhood ME/CFS. Researchers found that about one-third of children with ME/CFS had problems regulating their blood pressure and heart rate when standing up, a condition called orthostatic dysregulation. While some studies suggested increased sympathetic nervous system activity, the findings were not consistent across all research.

Autonomic Nervous System

E3 PreliminaryReviewPEM unclearReview-Narrative

[History of chronic fatigue syndrome].

Hashimoto, Nobuya·Nihon rinsho. Japanese journal of clinical medicine·2007

This article reviews the history of ME/CFS, showing that conditions with similar symptoms have existed for hundreds of years under different names like neurasthenia and myalgic encephalomyelitis. A major outbreak at Lake Tahoe in the 1980s brought modern attention to the disease, but doctors realized that not all patients with CFS symptoms actually had evidence of EBV infection, suggesting the disease is more complex than a simple viral cause. The authors explain how understanding this history can help develop better diagnostic guidelines for the condition.

Diagnostics

E3 PreliminaryBehavioralPEM not requiredCase-Control

[Usefulness of growth chart in children and adolescents with chronic fatigue syndrome].

Oki, Junichi, Okubo, Jun·Nihon rinsho. Japanese journal of clinical medicine·2007

This small study looked at growth charts from three young people with chronic fatigue syndrome to see if the charts could help identify what triggered their illness. The researchers found that life events—like overexercise, family stress, or infection—appeared before symptoms like extreme tiredness, nausea, and sleep problems started. While growth charts alone cannot predict who will develop ME/CFS, they may help doctors spot important life changes that happened around the time symptoms began.

E3 PreliminaryCohortPEM unclearCross-Sectional

'What is it like to have ME?': the discursive construction of ME in computer-mediated communication and face-to-face interaction.

Guise, Jennifer, Widdicombe, Sue, McKinlay, Andy·Health (London, England : 1997)·2007

This study examined how people with ME/CFS describe their illness when talking online and face-to-face. Researchers analyzed conversations from 49 internet users and 7 people in support groups to understand how patients talk about their condition. They found that people consistently describe ME/CFS as serious, mysterious, and not caused by psychological factors—ways of talking that help them counter misconceptions and explain why their illness isn't their fault.

E3 PreliminaryCohortPEM not requiredCase-Control

[A new treatment: thermal therapy for chronic fatigue syndrome].

Masuda, Akinori, Munemoto, Takao, Tei, Chuwa·Nihon rinsho. Japanese journal of clinical medicine·2007

Researchers tested far-infrared sauna therapy on 13 ME/CFS patients. Two patients experienced dramatic improvements in fatigue, pain, and fever, and were able to stop taking prednisolone and return to normal activities within 6 months. The remaining 11 patients also reported improvements in fatigue and pain, with additional benefits including relaxation and reduced depression symptoms.

E3 PreliminaryReviewPEM not requiredReview-Narrative

[Antinuclear antibodies in patients with chronic fatigue syndrome].

Nishikai, Masahiko·Nihon rinsho. Japanese journal of clinical medicine·2007

This review examined whether people with ME/CFS have specific antibodies (immune proteins) that attack their own body cells. Researchers found that 15-25% of ME/CFS patients had these antibodies, but the patterns varied widely and were generally weak. A few new antibodies specific to ME/CFS were identified, with one type appearing in 13% of patients studied and linked to severe fatigue and concentration problems.

Immune System

E3 PreliminaryMechanismPEM not requiredMechanistic

Sense of effort during a fatiguing exercise protocol in chronic fatigue syndrome.

Wallman, Karen E, Sacco, Paul·Research in sports medicine (Print)·2007

This study asked whether people with ME/CFS feel more effort when doing physical tasks compared to healthy people. Researchers had both groups perform a repetitive arm exercise for 45 minutes while rating how hard it felt. People with ME/CFS reported significantly higher effort levels and produced more force than controls, even though the task was the same for everyone.

Post-Exertional Malaise

E3 PreliminaryBehavioralPEM not requiredCross-Sectional

Brief report: The accuracy of parents for the thoughts and feelings of their adolescent suffering from chronic fatigue: a preliminary study of empathy.

Vervoort, Tine, Crombez, Geert, Buysse, Ann et al.·Journal of pediatric psychology·2007

This study looked at whether parents of teenagers with ME/CFS could accurately understand what their child was thinking and feeling. Researchers found that parents were less able to understand their teenager's thoughts and feelings about ME/CFS itself compared to other life situations. Interestingly, teenagers thought their mothers understood them better than their fathers did, even though fathers were actually just as accurate in understanding them.

E3 PreliminaryMechanismPEM not requiredObservational

[Chronic fatigue syndrome and herpesvirus reactivation].

Kondo, Kazuhiro·Nihon rinsho. Japanese journal of clinical medicine·2007

This study looked at whether two common viruses that hide dormant in our bodies (HHV-6 and HHV-7) wake up and become active during fatigue. Researchers found that healthy people shed more HHV-6 in their saliva when tired from work, but ME/CFS patients did not show this pattern. However, HHV-7 did increase in both groups, suggesting these viruses might be useful markers to measure fatigue objectively.

BiomarkersImmune System

E3 PreliminaryPEM unclear

Chronic fatigue syndrome after Q fever.

Ledina, Dragan, Bradarić, Nikola, Milas, Ivo et al.·Medical science monitor : international medical journal of experimental and clinical research·2007

Q fever is an infection caused by bacteria that can spread from animals to people. While most people recover from acute Q fever, a few develop chronic fatigue that looks like ME/CFS. This report describes three patients who developed post-Q-fever fatigue syndrome and were treated with antibiotics, with mixed results—two improved but one did not.

E3 PreliminaryMechanismPEM unclearCross-Sectional

Abnormal thermoregulatory responses in adolescents with chronic fatigue syndrome: relation to clinical symptoms.

Wyller, Vegard Bruun, Godang, Kristin, Mørkrid, Lars et al.·Pediatrics·2007

This study looked at how the body controls temperature in adolescents with ME/CFS compared to healthy teenagers. Researchers found that people with ME/CFS have abnormal responses to temperature changes, with their bodies struggling to regulate heat and cold properly. The study suggests this problem may be related to dysfunction in the nervous system's control of stress hormones like adrenaline.

Autonomic Nervous System

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Evidence browser

[Chronic fatigue syndrome in a 15-year-old girl].

Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndrome.

Drug residues store in the body following cessation of use: impacts on neuroendocrine balance and behavior--use of the Hubbard sauna regimen to remove toxins and restore health.

Myalgic encephalomyelitis: a review with emphasis on key findings in biomedical research.

[Overview of psychiatric therapy for chronic fatigue syndrome].

Orthostatic panic attacks among Vietnamese refugees.

[Clinical features of chronic fatigue syndrome--symptoms].

Successful use of a primary care practice-specialty collaboration in the care of an adolescent with chronic fatigue syndrome.

The chronic fatigue syndrome: a comparative pathway analysis.

[Autonomic function and child chronic fatigue syndrome].

[History of chronic fatigue syndrome].

[Usefulness of growth chart in children and adolescents with chronic fatigue syndrome].

'What is it like to have ME?': the discursive construction of ME in computer-mediated communication and face-to-face interaction.

[A new treatment: thermal therapy for chronic fatigue syndrome].

[Antinuclear antibodies in patients with chronic fatigue syndrome].

Sense of effort during a fatiguing exercise protocol in chronic fatigue syndrome.

Brief report: The accuracy of parents for the thoughts and feelings of their adolescent suffering from chronic fatigue: a preliminary study of empathy.

[Chronic fatigue syndrome and herpesvirus reactivation].

Chronic fatigue syndrome after Q fever.

Abnormal thermoregulatory responses in adolescents with chronic fatigue syndrome: relation to clinical symptoms.

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