E0 ConsensusReviewPEM not requiredSystematic-Review
Chronic fatigue syndrome and circulating cytokines: A systematic review.
Blundell, S, Ray, K K, Buckland, M et al.·Brain, behavior, and immunity·2015
Researchers reviewed 38 studies looking at whether immune proteins called cytokines are elevated in people with ME/CFS. They found that one specific cytokine, TGF-β, was consistently higher in people with ME/CFS compared to healthy people in about 63% of studies. However, most other immune proteins measured were normal, and exercise did not change cytokine levels differently between people with ME/CFS and healthy controls.
Immune SystemPost-Exertional Malaise