ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

5581–5600 of 6,188 studies

E3 PreliminaryCohortPEM not requiredCase-Control

Peripheral vestibular dysfunction in chronic fatigue syndrome.

Palaniappan, Rudrapathy, Sirimanna, Tony·International journal of pediatric otorhinolaryngology·2002

This study describes a 12-year-old boy with ME/CFS who experienced dizziness caused by a problem with the balance system in his inner ear (his left vestibular system). The doctors found that specific tests could identify this balance problem, and that exercises designed to help retrain the balance system were an effective treatment. This case suggests that some people with ME/CFS who have dizziness might benefit from checking their balance system and doing targeted exercises.

E3 PreliminaryReviewPEM unclearReview-Narrative

Information from your family doctor. Chronic fatigue syndrome: how to help yourself.

American family physician·2002

This article from American Family Physician provides practical guidance for people with ME/CFS and their doctors about self-help strategies. It offers information to help patients understand their condition better and suggests ways they can manage their symptoms with support from their healthcare provider.

E3 PreliminaryReviewPEM unclearReview-Narrative

The chronic fatigue syndrome is a disease of the autonomic nervous system. Sometimes.

Freeman, Roy·Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2002

This review article examines whether ME/CFS might be caused by problems with the autonomic nervous system—the part of your body that controls automatic functions like heart rate and blood pressure. The author, Dr. Roy Freeman, discusses evidence suggesting that some ME/CFS patients do show signs of autonomic dysfunction, but emphasizes that this is not true for all patients with the condition.

Autonomic Nervous System

E3 PreliminaryCohortPEM not requiredCase-Control

The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: a case report.

Logan, Alan C, Beaulne, Tracey M·Alternative medicine review : a journal of clinical therapeutic·2002

This study describes one patient who had too many bacteria growing in their small intestine and was experiencing IBS-like symptoms. When treated with enteric-coated peppermint oil (a special form of peppermint that reaches the small intestine), the patient felt significantly better and had measurable improvements in digestive gas production. This suggests peppermint oil might work by reducing harmful bacteria in the gut.

E3 PreliminaryReviewPEM unclearReview-Narrative

Distinguishing Mars from Venus: emergence of gender biology differences in oral health and systemic disease.

Slavkin, Harold C·Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)·2002

This article examines how men and women differ in their health, including oral health and overall diseases. The authors note that women and men have different genetics, body chemistry, and hormones, which leads to different rates of certain illnesses like autoimmune diseases, osteoporosis, and chronic fatigue syndrome. Understanding these gender differences can help doctors provide better, more personalized care for women.

E3 PreliminaryCohortPEM unclearCross-Sectional

Women's experiences of stigma in relation to chronic fatigue syndrome and fibromyalgia.

Asbring, Pia, Närvänen, Anna-Liisa·Qualitative health research·2002

This study interviewed 25 women with ME/CFS or fibromyalgia about their experiences with stigma—being doubted, judged, or not taken seriously. Women reported that stigma was most common before they received a diagnosis, and that having many different symptoms made it harder for others to believe they were truly ill. People sometimes questioned whether the illnesses were real or blamed them on emotional problems rather than physical causes.

Diagnostics

E3 PreliminaryBehavioralPEM not requiredCase-Control

[Symptom or illness? The exhausting life of an adolescent with chronic fatigue syndrome].

Di Gallo, A·Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie·2002

This study describes the medical experience of a teenage boy diagnosed with chronic fatigue syndrome (CFS). The doctors examined questions about what causes CFS, how it develops, how to diagnose it, and what treatments might help. The case provides a detailed look at one patient's journey with this complex illness.

Diagnostics

E3 PreliminaryReviewPEM not requiredReview-Narrative

The intelligent body and its discontents.

Hyland, Michael E·Journal of health psychology·2002

This paper proposes that the whole body—not just the brain—can learn and process information like a complex computer system. When this body-wide system malfunctions, it can create widespread health problems distributed throughout the body rather than in one location. The authors suggest ME/CFS is an example of this type of whole-body dysfunction and may require different treatment approaches than traditional medicine typically offers.

E3 PreliminaryReviewPEM unclearReview-Narrative

Biorhythms and possible central regulation of magnesium status, phototherapy, darkness therapy and chronopathological forms of magnesium depletion.

Durlach, Jean, Pagès, Nicole, Bac, Pierre et al.·Magnesium research·2002

This paper proposes that magnesium deficiency may be linked to disrupted circadian rhythms (biological clocks) and could contribute to several conditions including ME/CFS, fibromyalgia, and sleep problems. The authors suggest that light therapy, dark therapy, and magnesium supplementation may help by affecting the body's internal clock and natural sleep hormone production.

Sleep

E3 PreliminaryReviewPEM unclearReview-Narrative

Chronic fatigue syndrome: evaluation and treatment.

Craig, Timothy, Kakumanu, Sujani·American family physician·2002

ME/CFS is a serious condition marked by extreme tiredness that doesn't go away, along with muscle pain, swollen lymph nodes, and feeling worse after physical activity. Doctors diagnose it mainly by ruling out other illnesses, since there's no single blood test or physical sign that definitively confirms it. Treatment is personalized and may include exercise, sleep improvements, diet changes, and medications like antidepressants.

Post-Exertional Malaise

E3 PreliminaryDiagnosticPEM not requiredMethods-Paper

Methodologic aspects of the study of modern-age diseases: the example of sick-building syndrome.

Thörn, Ake·International journal of occupational and environmental health·2002

This paper discusses challenges in studying conditions like ME/CFS that have many different symptoms but no clear physical test to diagnose them. The authors suggest that studying how these illnesses develop over time, through detailed interviews and case studies, may help us understand them better than traditional research methods that count statistics across large groups.

E3 PreliminaryBehavioralPEM not requiredCase-Control

Chronic fatigue syndrome and eating disorders: concurrence or coincidence?

Fisher, Martin, Krilov, Leonard R, Ovadia, Marc·International journal of adolescent medicine and health·2002

This study looked at four adolescent patients who had both an eating disorder and ME/CFS at the same time. In all four cases, the eating disorder appeared first, followed later by ME/CFS symptoms. The authors explored whether these two conditions might be related through common causes, whether an eating disorder could trigger ME/CFS, or whether they simply occurred together by chance.

Autonomic Nervous System

E3 PreliminaryReviewPEM not requiredReview-Narrative

Role of fatigue in limiting physical activities in humans with neuromuscular diseases.

Miller, Robert G·American journal of physical medicine & rehabilitation·2002

Fatigue in people with muscle and nerve diseases works differently than tiredness in healthy people, and scientists are now developing better tools to measure it. This paper reviews what we know about two types of fatigue: one that comes from the brain and nervous system (central fatigue) and one that comes from the muscles themselves (peripheral fatigue). The authors explain how these different types of fatigue affect people with conditions like ME/CFS, post-polio syndrome, and other neuromuscular diseases.

E3 PreliminaryReviewPEM unclearReview-Narrative

[On the history of the concept neurasthenia and its modern variants chronic-fatigue-syndrome, fibromyalgia and multiple chemical sensitivities].

Schäfer, M L·Fortschritte der Neurologie-Psychiatrie·2002

This article traces the history of a medical term called 'neurasthenia' that was used in the 1800s to describe people with severe tiredness and weakness. The author explains how this old concept disappeared from Western medicine but has reappeared in modern times under new names like Chronic Fatigue Syndrome, fibromyalgia, and multiple chemical sensitivities. The article suggests that cultural and social factors influence how these illnesses are recognized and named in different parts of the world.

E3 PreliminaryReviewPEM unclearReview-Narrative

Quality of life issues in patients with essential thrombocythemia and polycythemia vera.

Hoffman, Ronald·Seminars in oncology·2002

This article discusses how doctors should measure quality of life in patients with two rare blood disorders (essential thrombocythemia and polycythemia vera). The author explains that while treatments can control blood cell production and prevent some serious complications, they often cause side effects. The article suggests that doctors should use quality-of-life questionnaires to better understand whether treatments are truly helping patients feel better overall.

E3 PreliminaryReviewPEM unclearReview-Narrative

[Use of IVIG in secondary immunodeficiencies].

Zeman, Krzysztof, Lewandowicz-Uszyńska, Aleksandra·Postepy higieny i medycyny doswiadczalnej·2002

This review article examines whether intravenous immunoglobulin (IVIG)—a blood product containing antibodies—might help patients with weakened immune systems, including those with HIV and chronic fatigue syndrome. The authors looked at published research to understand when and how IVIG might be useful, particularly for people recovering from serious injuries, burns, or major surgery.

Immune System

E3 PreliminaryMechanismPEM requiredMechanistic

Activity rhythm degrades after strenuous exercise in chronic fatigue syndrome.

Ohashi, Kyoko, Yamamoto, Yoshiharu, Natelson, Benjamin H·Physiology & behavior·2002

This study looked at whether exhausting exercise disrupts the body's internal daily rhythm in people with ME/CFS. Researchers measured activity patterns in ME/CFS patients and healthy controls before and after a strenuous treadmill test. They found that ME/CFS patients' activity rhythms became abnormally lengthened (longer than 24 hours) after exercise, while healthy people's rhythms stayed normal—suggesting the body loses its ability to keep time after strenuous activity in ME/CFS.

Post-Exertional Malaise

E3 PreliminaryReviewPEM not requiredReview-Narrative

[Chronic fatigue syndrome: psychiatric perspectives].

Youssefi, M, Linkowski, P·Revue medicale de Bruxelles·2002

This review examines ME/CFS from a psychiatric perspective, looking at how mental health symptoms often occur alongside the physical illness. Many people with ME/CFS also experience depression, anxiety, or other mood problems, though it's unclear whether these conditions cause ME/CFS or develop because of living with a serious chronic illness. The authors discuss treatments that have shown promise, including talking therapy, exercise programs, and antidepressants when appropriate, while emphasizing that a supportive doctor-patient relationship is essential.

E3 PreliminaryReviewPEM unclearReview-Narrative

Chronic fatigue syndrome: probable pathogenesis and possible treatments.

Evengård, Birgitta, Klimas, Nancy·Drugs·2002

ME/CFS is a serious illness affecting about 1 in 200 people in Western countries, causing extreme tiredness that lasts at least 6 months along with problems thinking clearly, poor sleep, and pain. While doctors don't yet know exactly what causes it, research shows the immune system is overactive and certain brain functions are disrupted. Currently, talking therapy (cognitive behavioural therapy) can help improve quality of life, but scientists are still searching for more effective treatments.

Immune SystemPost-Exertional Malaise

E3 PreliminaryReviewPEM not requiredReview-Narrative

Chiari type I malformation revisited: diagnosis and treatment.

Cheng, Joseph S, Nash, John, Meyer, Glenn A·The neurologist·2002

Chiari type I is a condition where brain tissue (cerebellar tonsils) extends into the spinal canal, potentially compressing the lower brain and upper spinal cord. This article reviews how doctors diagnose and treat this condition, and discusses possible links between Chiari I and ME/CFS, fibromyalgia, and other neurological symptoms. The authors note that in severe cases, Chiari I can cause permanent nerve damage, but better imaging and treatments are being developed.

Autonomic Nervous System

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Evidence browser

Peripheral vestibular dysfunction in chronic fatigue syndrome.

Information from your family doctor. Chronic fatigue syndrome: how to help yourself.

The chronic fatigue syndrome is a disease of the autonomic nervous system. Sometimes.

The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: a case report.

Distinguishing Mars from Venus: emergence of gender biology differences in oral health and systemic disease.

Women's experiences of stigma in relation to chronic fatigue syndrome and fibromyalgia.

[Symptom or illness? The exhausting life of an adolescent with chronic fatigue syndrome].

The intelligent body and its discontents.

Biorhythms and possible central regulation of magnesium status, phototherapy, darkness therapy and chronopathological forms of magnesium depletion.

Chronic fatigue syndrome: evaluation and treatment.

Methodologic aspects of the study of modern-age diseases: the example of sick-building syndrome.

Chronic fatigue syndrome and eating disorders: concurrence or coincidence?

Role of fatigue in limiting physical activities in humans with neuromuscular diseases.

[On the history of the concept neurasthenia and its modern variants chronic-fatigue-syndrome, fibromyalgia and multiple chemical sensitivities].

Quality of life issues in patients with essential thrombocythemia and polycythemia vera.

[Use of IVIG in secondary immunodeficiencies].

Activity rhythm degrades after strenuous exercise in chronic fatigue syndrome.

[Chronic fatigue syndrome: psychiatric perspectives].

Chronic fatigue syndrome: probable pathogenesis and possible treatments.

Chiari type I malformation revisited: diagnosis and treatment.

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