ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

61–73 of 73 studies

E3 PreliminaryReviewPEM unclearReview-Narrative

Considerations for Long COVID Rehabilitation in Women.

Verduzco-Gutierrez, Monica, Fleming, Talya K, Azola, Alba M·Physical medicine and rehabilitation clinics of North America·2025

Long COVID is a condition where people experience ongoing symptoms weeks or months after a COVID-19 infection. This review examines how rehabilitation can help long COVID patients, with special attention to how women are affected differently. The authors emphasize that personalized treatment plans involving multiple types of therapy and healthcare teamwork are important for recovery.

Long COVID Overlap

E3 PreliminaryReviewPEM unclearReview-Narrative

Developing a clinical-pathological framework of long COVID-related fatigue applied to public safety workers.

Lofrano-Porto, Adriana, D'Isabel, Susanne, Smith, Denise L·Frontiers in medicine·2024

This article reviews what we know about long COVID fatigue, especially in firefighters and other public safety workers. The authors explain why fatigue after COVID is so hard to diagnose and treat, since patients often look healthy on the outside even though they feel extremely tired. They describe possible biological reasons for this fatigue and discuss why it matters for workers whose jobs require them to be physically and mentally alert.

DiagnosticsLong COVID Overlap

E3 PreliminaryReviewPEM unclearReview-Narrative

[Myalgic encephalomyelitis/chronic fatigue syndrome as a complication of COVID-19 post-acute syndrome in adults. Bibliographic Review].

Carrillo Uguña, Miguel Esteban, Orellana Romero, Paula Michelle·Vertex (Buenos Aires, Argentina)·2024

This review examines how some COVID-19 survivors develop symptoms very similar to ME/CFS weeks or months after their acute infection ends. The authors found that over 87% of COVID-19 patients still experience at least one symptom two months after infection, and some of these symptoms match what ME/CFS patients experience. The study suggests that COVID-19 may trigger ME/CFS-like illness in some adults, similar to how other infections have been linked to ME/CFS in the past.

Long COVID OverlapPost-Exertional Malaise

E3 PreliminaryGuidelinePEM unclearGuideline

Designing and optimizing clinical trials for long COVID.

Vogel, Julia Moore, Pollack, Beth, Spier, Ezra et al.·Life sciences·2024

This study looked at all the clinical trials being tested for Long COVID on a public database and found that most trials are not well-designed or testing treatments that have enough evidence to justify testing. The researchers recommend that future trials should test actual medications that might cure Long COVID, be able to run remotely so sick patients don't have to travel, compare Long COVID to similar illnesses like ME/CFS, include diverse patients of all backgrounds and illness levels, and involve patients as research partners.

Long COVID Overlap

E3 PreliminaryCommentaryPEM unclearEditorial

Long COVID: a new disease?

Mirofsky, Matias, Catalano, Hugo·Medicina·2024

This article discusses whether Long COVID should be considered a new disease and examines how medical systems can avoid overtreatment. The authors note that Long COVID shares similarities with other post-infection illnesses like ME/CFS and fibromyalgia, and they argue that careful, thoughtful medical care is important to prevent unnecessary treatments from making patients worse.

Long COVID Overlap

E3 PreliminaryReviewPEM unclearReview-Narrative

Fatigue in Post-Acute Sequelae of Coronavirus Disease 2019.

Abbott, Zachary, Summers, William, Niehaus, William·Physical medicine and rehabilitation clinics of North America·2023

This review examines fatigue experienced by people recovering from COVID-19, which can be severe and long-lasting. The authors explain that this fatigue likely has multiple different causes in different people, rather than one single explanation. They suggest that treatments work best when doctors identify what might be causing each patient's fatigue and create personalized activity plans that gradually increase over time.

Long COVID Overlap

E3 PreliminaryReviewPEM unclearReview-Narrative

Long COVID: major findings, mechanisms and recommendations.

Davis, Hannah E, McCorkell, Lisa, Vogel, Julia Moore et al.·Nature reviews. Microbiology·2023

Long COVID is a serious illness affecting at least 10% of people who had COVID-19, with an estimated 65 million people worldwide experiencing it. The condition causes over 200 different symptoms affecting many body systems, similar to ME/CFS and other post-viral illnesses. This review examines what scientists have learned about Long COVID's causes and effects, though better diagnostic tests and treatments are still urgently needed.

Long COVID OverlapPost-Exertional Malaise

E3 PreliminaryReviewPEM unclearReview-Narrative

Unexplained post-acute infection syndromes.

Choutka, Jan, Jansari, Viraj, Hornig, Mady et al.·Nature medicine·2022

This review explains that several different infections—not just COVID-19—can sometimes cause long-lasting illness in some people who recover from the initial infection. These post-infection conditions share similar symptoms and overlap with ME/CFS, suggesting they might have common underlying causes that scientists don't yet understand. The authors argue that researchers need to invest more effort in understanding why and how these mysterious long-term illnesses develop.

Long COVID Overlap

E3 PreliminaryGuidelinePEM unclearGuideline

Postacute Sequelae of SARS-CoV-2 Infection-Lessons Learned From a Coordinated Health System Response.

Ganesh, Ravindra, Vanichkachorn, Greg S, Munipalli, Bala et al.·Mayo Clinic proceedings. Innovations, quality & outcomes·2022

This study describes how Mayo Clinic, a large healthcare system across five states, created a coordinated plan to help patients recover from long-term COVID-19 symptoms. Doctors from many different specialties worked together to develop consistent guidelines for evaluating and treating these patients. The system includes specialized appointment forms, sample collection for research, and dedicated treatment programs to provide better care.

Long COVID Overlap

E3 PreliminaryReviewPEM unclearReview-Narrative

COVID-19 and chronic fatigue syndrome: An endocrine perspective.

Bansal, Rashika, Gubbi, Sriram, Koch, Christian A·Journal of clinical & translational endocrinology·2022

Some people who recover from COVID-19 experience long-lasting exhaustion and other debilitating symptoms similar to ME/CFS. This review examines how COVID-19 might affect the body's hormone systems, particularly the glands that control stress response and energy levels. The authors suggest doctors should check patients' hormone levels as part of their care plan.

Endocrine DisruptionLong COVID Overlap

E3 PreliminaryCohortPEM not requiredCase-Control

New Clinical Phenotype of the Post-Covid Syndrome: Fibromyalgia and Joint Hypermobility Condition.

Gavrilova, Natalia, Soprun, Lidiia, Lukashenko, Maria et al.·Pathophysiology : the official journal of the International Society for Pathophysiology·2022

This study describes a pattern found in some people who developed fibromyalgia (widespread pain) after COVID-19 infection. The researchers noticed that young women with loose, flexible joints who had COVID-19 and a specific tendon injury were more likely to develop fibromyalgia along with signs of inflammation. The study presents three patient cases that fit this pattern, suggesting COVID-19 may trigger fibromyalgia in people whose connective tissues are already prone to damage.

Immune SystemLong COVID Overlap

E3 PreliminaryPEM unclear

Myalgic encephalomyelitis/chronic fatigue syndrome post coronavirus disease 2019.

Kusama, Yoshiki, Fukui, Sadahiro, Maruyama, Makiko et al.·Pediatrics international : official journal of the Japan Pediatric Society·2022

This study examines whether ME/CFS can develop in children after they have COVID-19. The researchers reviewed existing information about how post-COVID conditions might lead to ME/CFS symptoms in young patients. This is important because understanding the link between COVID-19 and ME/CFS could help doctors recognize and support children who develop this condition after a viral infection.

Long COVID Overlap

E3 PreliminaryCommentaryPEM unclear

Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome.

Komaroff, Anthony L, Lipkin, W Ian·Trends in molecular medicine·2021

This article compares myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) with long COVID to see if they might share similar causes. The authors suggest that some people who develop long COVID symptoms—like persistent fatigue, cognitive problems, and pain—may experience similar biological problems to those seen in ME/CFS. Understanding these shared mechanisms could help doctors better treat both conditions.

Energy MetabolismLong COVID Overlap

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Considerations for Long COVID Rehabilitation in Women.

Developing a clinical-pathological framework of long COVID-related fatigue applied to public safety workers.

[Myalgic encephalomyelitis/chronic fatigue syndrome as a complication of COVID-19 post-acute syndrome in adults. Bibliographic Review].

Designing and optimizing clinical trials for long COVID.

Long COVID: a new disease?

Fatigue in Post-Acute Sequelae of Coronavirus Disease 2019.

Long COVID: major findings, mechanisms and recommendations.

Unexplained post-acute infection syndromes.

Postacute Sequelae of SARS-CoV-2 Infection-Lessons Learned From a Coordinated Health System Response.

COVID-19 and chronic fatigue syndrome: An endocrine perspective.

New Clinical Phenotype of the Post-Covid Syndrome: Fibromyalgia and Joint Hypermobility Condition.

Myalgic encephalomyelitis/chronic fatigue syndrome post coronavirus disease 2019.

Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome.

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