ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

61–80 of 213 studies

E2 ModerateCohortPEM not requiredCross-Sectional

Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome.

Schoeman, Elizna M, Van Der Westhuizen, Francois H, Erasmus, Elardus et al.·BMC medical genetics·2017

This study examined the DNA inside the energy-producing parts of cells (mitochondria) in 93 ME/CFS patients from the UK and South Africa. The researchers looked for specific mutations that are known to cause mitochondrial disease. They found that these known harmful mutations were not present in the ME/CFS patients studied, suggesting that ME/CFS is not caused by these well-established mitochondrial mutations.

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Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome.

Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome.

Evidence of mitochondrial dysfunction and impaired redox signalling in a subgroup of patients with myalgic encephalomyelitis/chronic fatigue syndrome

Mitochondrial DNA variants correlate with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome.

Genetic evaluation of AMPD1, CPT2, and PGYM metabolic enzymes in patients with chronic fatigue syndrome.

Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles.

Association of mitochondrial DNA variants with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) symptoms.

Increased prevalence of two mitochondrial DNA polymorphisms in functional disease: Are we describing different parts of an energy-depleted elephant?

Irritable bowel syndrome may be associated with maternal inheritance and mitochondrial DNA control region sequence variants.

HIV-associated fatigue in the era of highly active antiretroviral therapy: novel biological mechanisms?

Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology.

The assessment of the energy metabolism in patients with chronic fatigue syndrome by serum fluorescence emission.

Mitochondrial dysfunction and the pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

Long-chain acylcarnitine deficiency in patients with chronic fatigue syndrome. Potential involvement of altered carnitine palmitoyltransferase-I activity.

Mitochondrial enzymes discriminate between mitochondrial disorders and chronic fatigue syndrome.

Chronic fatigue syndrome is associated with metabolic syndrome: results from a case-control study in Georgia.

Visible and near-infrared spectral changes in the thumb of patients with chronic fatigue syndrome.

Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome.

Chronic fatigue syndrome and mitochondrial dysfunction.

Physiological cost of walking in those with chronic fatigue syndrome (CFS): a case-control study.

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