Do people with ME/CFS and joint hypermobility represent a disease subgroup? An analysis using registry data.
Mudie, Kathleen, Ramiller, Allison, Whittaker, Sadie et al.·Frontiers in neurology·2024
This study looked at whether ME/CFS patients with loose, flexible joints (joint hypermobility) form a distinct group with different symptoms and health impacts. Researchers surveyed 815 ME/CFS patients and found that about 16% had joint hypermobility. These patients reported worse quality of life, more pain, and more symptoms affecting their nervous system, thinking, digestion, and muscles compared to ME/CFS patients without joint hypermobility.