E1 ReplicatedTrialPEM not requiredRCT
Use of lisdexamfetamine dimesylate in treatment of executive functioning deficits and chronic fatigue syndrome: a double blind, placebo-controlled study.
Young, Joel L·Psychiatry research·2013
This study tested whether a medication called lisdexamfetamine (LDX), which affects brain chemicals related to focus and attention, could help people with ME/CFS who struggle with executive functioning—skills like planning, organizing, and decision-making. Twenty-six participants took either the medication or a placebo for 6 weeks, and those on LDX showed significantly better improvements in executive functioning, fatigue, and pain compared to placebo.
Cognitive Impairment