E3 PreliminaryCommentaryPEM unclearEditorial
Chronic fatigue syndrome--a neuroimmunological model.
Arnett, S V, Alleva, L M, Korossy-Horwood, R et al.·Medical hypotheses·2011
This review suggests that ME/CFS may develop when the body has trouble controlling infections early on, leading to long-term inflammation in the brain. The authors propose that this inflammatory process—involving both the immune system and the nervous system—could explain many ME/CFS symptoms and why more women are affected than men. They also suggest that anti-inflammatory treatments targeting a protein called TNF might help patients.
NeuroinflammationImmune System