Associations Between Cognitive Performance and Pain in Chronic Fatigue Syndrome: Comorbidity with Fibromyalgia Does Matter.
Ickmans, Kelly, Meeus, Mira, De Kooning, Margot et al.·Pain physician·2015
This study looked at whether pain and thinking problems are connected in people with ME/CFS, and whether having fibromyalgia alongside ME/CFS changes this relationship. Researchers tested 48 patients with ME/CFS (some with fibromyalgia, some without) and 30 healthy people on memory and attention tasks, then measured their pain responses. They found that the type of pain problem matters: in patients with both conditions, a specific pain-processing difference predicted thinking problems, while in ME/CFS-only patients, reported pain levels predicted thinking problems.